99>I have cancer and when I asked my oncologist for anti-anxiety medication he said he would give me enough for one month but that I need to find another Dr. to prescribe them after that. I have had anxiety and panic attacks for years, and now after being diagnosed with cancer it's gotten worse. I take prozac but it only helps my depression. Thanks in advance for answering!
Reply:Who ever orders your prozac is the doctor you should see about something for anxiety.
Reply:Yes. Past a couple of partially effective treatments, it is time to see a specialist, no matter the area of treatment.
Reply:A PCP should be able to prescribe them to you. You will need to stay in regular contact/visits with him/her due to the fact that ante-anxiety meds are considered highly addictive. You are in my thoughts
Reply:you could ask your PCP for an "as needed" anti-anxiety medication. if what your oncologist prescribed worked ask your pcp for a refill.
Reply:As a fellow sufferer of anxiety and panic attacks, I can tell you that your PCP can prescribe them. Be sure to tell him/her EVERYTHING, so he can decide which med is best for you. Good luck, hon. :)
Reply:No you do not have 2 see a psychiatrist your doctor can prescribe anything except anti-psychotic or anti-schizophrenic drugs
Reply:PCP will be able to prescibe it, but may try very hard to get you to try a little therapy. There are lots of different kinds of therapy, like talk therapy with a psychatrist or psychologist or group therapy with people who are going through similar stuff. I wouldn't want to be solely dependent on my family, they depend on me too much. You may benefit very much by talking to the PCP about this and seeing what he says. Even if you decide to try some therapy, that doesn't mean you'll be leaving without a 'script.
Reply:You need to talk to someone who knows psychotropics. they would know how they might interact with any chemotherapy or other meds that you might be taking. They would also know best which medicines will work best with the ones that you're already taking. in fact I would ask my oncologist to direct me to a therapist who's used to dealing with cancer patients. I know that there are psychiatrist who do this as I had one when I was diagnosed about ten years ago. They understood what I was dealing with and they knew which medications where more likely to work. I will keep you in my thoughts.
Thursday, July 30, 2009
Do I have to go to a psychiatrist to be prescribed anti-anxiety meds or can/will my PCP prescribe them?
98>I have cancer and when I asked my oncologist for anti-anxiety medication he said he would give me enough for one month but that I need to find another Dr. to prescribe them after that. I have had anxiety and panic attacks for years, and now after being diagnosed with cancer it's gotten worse. I take prozac but it only helps my depression. Thanks in advance for answering!
Reply:Any doctor can prescribe medications. But your best bet is to see a psychiatrist. There are many different meds for different conditions, and a psychiatrist is likely to know more about more of them than a general doctor.
You might want to find a talk therapist or a support group to talk out your problems too. Cancer is a really heavy thing to handle on your own.
I wish you the best. Take good care of yourself in all kinds of ways.
Reply:I think any doctor can prescribe anti-anxiety meds.
Reply:Your PCP can prescribe any and all medications. A psychiatrist is a licensed medical doctor who furthered their career by studying psychiatry after getting their medical degree.
Reply:You don't have to go to a Psychiatrist to be prescribed anti-anxiety meds. Other doctors can do that for you. Best of Luck!
Reply:Any doctor can prescribe medications. But your best bet is to see a psychiatrist. There are many different meds for different conditions, and a psychiatrist is likely to know more about more of them than a general doctor.
You might want to find a talk therapist or a support group to talk out your problems too. Cancer is a really heavy thing to handle on your own.
I wish you the best. Take good care of yourself in all kinds of ways.
Reply:I think any doctor can prescribe anti-anxiety meds.
Reply:Your PCP can prescribe any and all medications. A psychiatrist is a licensed medical doctor who furthered their career by studying psychiatry after getting their medical degree.
Reply:You don't have to go to a Psychiatrist to be prescribed anti-anxiety meds. Other doctors can do that for you. Best of Luck!
The Day the FDA Took a Cancer Cure Away :?
97>The Day the FDA Took a Cancer Cure Away
by Bill Sardi
by Bill Sardi
DIGG THIS
Excerpt from the book: You Don鈥檛 Have To Be Afraid Of Cancer Any More, by Bill Sardi 漏 2007
The most significant event in the recent history of prostate cancer care has been the introduction, for a time, of a combination herbal remedy that caught cancer doctors by surprise. This herbal dietary supplement captured the attention of prostate cancer patients and doctors alike. The herbal combo began extending the lives of otherwise helpless prostate cancer patients facing the advanced life-threatening form of their disease. How the cancer industry responded to this development, and the events surrounding the decision to withdraw this herbal formula from the marketplace, despite its unprecedented effectiveness, reveals much about the dismal state of cancer care in America. One cannot read this account without becoming outraged at the final outcome.
An herbal remedy captivates
About 230,000 men learn of their prostate cancer each year in the United States. Among them is a group of about 40,000 men who face the aggressive form of the disease where the cancer has begun to spread to bone and other organs, threatening their lives.
In the mid-1990s, men with this progressive form of prostate cancer found a multi-herbal remedy to be quite effective in subduing the pain, inflammation and spread of prostate cancer. Sadly, the product was suddenly recalled for mislabeling problems, never to be re-introduced.
The whole unfortunate tale is indicative of what is going on in the cancer care industry today and worthy of re-analysis here. This is a story that every male with prostate cancer needs to read and understand. If you are familiar with this story, new data places a different ending to the story.
The saga begins
Long about 1996, a research scientist by the name of Sophie Chen, PhD, a graduate of Columbia University and post-doctoral fellow at Cornell University, who spent 14 years working for pharmaceutical companies (Merck Sharp %26amp; Dohme and Bayer USA), developed a multi-herbal product for males with advanced prostate cancer. It was named PC-SPES. The PC stood for prostate cancer, and "spes" is the Latin word for hope.
In 1988, Dr. Chen began her research into the role that natural herbs can play in healing and curing cancer, and obtained a dozen U.S. patents. In 1993, Dr. Chen co-founded the International Medical Research Corporation with "Allan" Xuhui Wang, MD, and John Chen (her brother), which did business under the name BotanicLab, the maker of PC-SPES.
Chen and Wang, who is also an herbalist, collaborated to modify an existing herbal formula used in China to treat urologic problems, which became the PC-SPES product. The first patient to use it was Chen鈥檚 brother-in-law, a physician in Taiwan with advanced prostate cancer who was alive and well 10 years later. [Journal National Cancer Institute 94: 1266-68, 2002]
Over time Dr. Chen had secured research grants from the National Cancer Institute and prostate cancer survivor/investor Michael Milken鈥檚 CaP CURE organization. Eventually an $8 million study grant from the National Institutes of Health was obtained, but the study never took place due to product quality problems. [PSA Rising, Dec. 19, 2003]
Many urologists and oncologists believed the herbal mix was prolonging their patients鈥?lives. Over 100 studies were published, validating its beneficial effects.
PC-SPES got spiked
A report published in the Journal of the National Cancer Institute in 2002 said: "PC-SPES was poised to become the first cancer treatment to emerge from the realm of alternative medicine, pass rigorous clinical testing, and add a powerful natural weapon to the oncologist鈥檚 arsenal."
As positive as the reports were for PC-SPES, there were nagging reports of side effects. Doctors began to suspect that the side effects caused by PC-SPES were similar to those produced by diethylstilbestrol (DES), a testosterone inhibitor that has been used to treat prostate cancer for decades.
The spiking of PC-SPES with drug molecules wasn鈥檛 apparent at first. A study published in 1998 found estrogen-like effects, but couldn鈥檛 identify the molecule involved. The study didn鈥檛 find any DES in PC-SPES at that time. [New England Journal Medicine 339: 785-91, Sept. 17, 1998] Chen denied the presence of any ingredients not on the label. Three times the California FDA tested PC-SPES and found no contamination, but utilized testing methods that could not detect minute amounts.
Then, as reports of side effects began to accumulate in 2001, some men suddenly noticed PC-SPES stopped working for them. PSA levels started to rise. Also a few cases of hemorrhaging were reported. Trace amounts of a blood thinner (warfarin) had been added to subsequent batches of PC-SPES in an apparent effort to counter reported blood clots.
It was later found that some batches of PC-SPES given to men in a comparative study contained from 0.01 to 3.1 % of DES. [Canadian Journal Urology 9: 1684-88, 2002] However, this wasn鈥檛 considered to be sufficient to cause the side effects being reported, in particular, the reports of blood clots.
Patients take charge
Cancer patients were communicating with each other via the internet, learning of the rising PSA levels among PC-SPES users.
Susan Domizi, wife of a Connecticut man taking PC-SPES, sent samples of the product to a laboratory and found it contained small amounts of DES. A second study also found DES. [International Journal Oncology 20: 583-88, 2002] By October of 2001, doctors had published a case of severe hemorrhaging associated with PC-SPES that was aired in the New England Journal of Medicine. [New England Journal Medicine 345: 1213-14, 2001]
Then the State of California FDA returned to BotanicLab to conduct more sensitive tests and surprisingly found DES in the same lots they had tested before, as well as the presence of another drug, warfarin (coumadin), a blood thinner. Retrospective tests now showed the product had been spiked with DES since 1996, and when side effects were reported, subsequent batches of PC-SPES displayed lower doses of DES, and then eventually the blood thinner, as if someone was attempting to limit the side effects. Sophie Chen responded by saying that none of the drugs was present in therapeutic doses and that "lots without DES worked equally well."
The eight herbs in PC-SPES
The Added Drug Ingredients
Licorice root
Reishi mushroom
Chrysanthemum
Dyers woad
Rabdosia
Saw palmetto
Baikal skullcap
Ginseng
Diethylstibestrol (DES) (testosterone interruptor)
Indomethacin (anti-inflammatory)
Warfarin (blood thinner)
Breakthrough in process
Whatever ingredients were in PC-SPES, they were producing a breakthrough in prostate cancer treatment all the while the product was being slammed for adulteration.
Michael Cook is an example. A 49-year-old who was diagnosed with prostate cancer at age 44, his tumors had spread to his ribs and pelvis. PC-SPES dropped his PSA from 80 to 0.2. "I鈥檝e been on PC-SPES for three years now, and I seem to be in complete remission," said the patient. [LA Times Oct. 21, 2000]
A group of men with prostate cancer, called UsToo, reported that their members maintained a low PSA concentration with PC-SPES in two successive surveys (88% and 93%). "Even though there were some side effects, a great majority of men are realizing good PSA control while taking the capsules, with some users now into their fourth year of PC-SPES use," said their report. [Molecular Urology 4: 289-91, 2000]
Moreover, a study conducted by Eric Small, MD and William Oh, MD at the University of California at San Francisco, showed that PC-SPES produced a 47% response rate compared to just 28% for diethylstiberstrol alone, and reduced PSA levels by more than 80% in all of their prostate cancer patients, with one patient experiencing complete disappearance of a bladder mass. In Dr. Small and Oh鈥檚 study involving 37 patients, three experienced blood clots. Side effects, however, were deemed to be "acceptable." [Journal Clinical Oncology 18: 3595-3603, 2000; Urology 57: 122-26, 2001]
A report in the Journal of Urology stated the side effect profile of PC-SPES was "comparable to estrogen treatment," with 42% experiencing nipple tenderness, 8% breast enlargement and 7% hot flashes. [Journal Urology 164: 1229-34, 2000]
Dr. Charles Myers of the American Institute for Diseases of the Prostate, in Charlottesville, Virginia, reported the case of a man whose PSA was nearly 3,000, an alarming level, but after taking PC-SPES it fell rapidly to below 1. Dr. Myers called PC-SPES "probably the most active agent" for treating prostate cancer in patients who no longer get results from conventional, hormone-blocking drugs. [Wall Street Journal May 26, 2002]
Still a mystery
Since no proof existed to show that BotanicLab had purchased any of these drug molecules, the blame for adulteration was cast upon sources of the herbs in China. Chen stated that she was not personally involved in mixing the company鈥檚 products, saying she was in New York conducting research most of the time, not in their Brea, California headquarters.
But Chen also contradicted herself when she said she had tested the herbal products herself and they were pure prior to encapsulation. She claimed the alcohol extraction of the herbs was conducted by companies in China, not in the United States. One of those suppliers in China also processed pharmaceuticals and could have been to blame. But they would have had to know what was going on in the United States to alter the product as they did.
Strangely, the Washington Post report stated that BotanicLab had conducted tests on its own in 2002 and determined bulk herbs coming into the country were free of pharmaceuticals, while packaged products leaving the Brea facility were adulterated. The Washington Post report said: "Tests conducted after BotanicLab shut down showed changes in pharmaceutical ingredients over time that the people suing BotanicLab regard as evidence of a conscious effort to manage troublesome side effects."
Blood clots are common in cancer patients, so this problem may not be attributed to PC-SPES. [Medicine 56: 1-37, 1977] But the addition of the anti-clotting drug warfarin, and the cases of hemorrhage, were certainly a concern.
The penalties
It took five years to shut down BotanicLab. PC-SPES was voluntarily recalled in 2002. Under agreements, John Chen, sister Sophie Chen, and Allan Xuhui Wang admitted to single misdemeanors involving the marketing of misbranded and adulterated food. Their defunct company pleaded no contest to the felony count of producing a product that presents a danger to the public. The corporation agreed to pay $350,000, the Chen鈥檚 agreed to pay $46,500 each, and Wang agreed to pay $56,500. Cancer survivors who had used PC SPES filed a class-action lawsuit against BotanicLab.
Patients sue
Later patients even sued the Milken Prostate Cancer Foundation. "Giving people prescription drugs without their knowledge is insane. It is total fraud," a woman was quoted as saying in a Washington Post article. [Washington Post, Sept. 5, 2004]
What caused the beneficial effects?
In 2000, researchers at Columbia University reported that "estrogen-like activity is not its [PC-SPES鈥橾 sole mechanism of action." [Journal Urology 164: 1229-34, 2000]
Investigators at New York Medical College obtained samples of single herb extracts used in the PC-SPES product and determined that no single herb could exert the reductions in PSA and testosterone reported in other studies. The authors of that study said "PC-SPES should be considered a single function unit since the combination of its biological properties appears to be more effective than its individual components." [International Journal Oncology 20: 583-88, 2002]
Dr. Oh stated there was something else in PC-SPES causing the beneficial results. Another study found that men taking nine PC-SPES capsules a day could get as much as 0.5 mg of DES per day, compared to the 3.0 mg used in the comparative study of the two drugs. So it appeared a small amount of DES was being added intentionally without being identified on the product label.
The cost
About 10,000 men in advanced stages of prostate cancer were estimated to be taking 6-9 capsules of PC-SPES per day at a retail cost ranging from $400 to $500 per month. An attorney estimated BotanicLab may have taken in $50 million before it was shut down.
For comparison, Canadian pharmacies are selling Lupron kits for $325-486. Lupron stops production of testosterone by the testes. Side effects with Lupron include breast enlargement and decreased libido, similar to those produced by PC-SPES. Over $876 million of Lupron was sold in 2004. Yet one physician, Glenn Bubley, MD, of Harvard Medical School was quoted as saying the manufacturer of PC-SPES "is making more money than God." [WebMD August 31, 2000] Another comparison: a 10-milliliter dose of Honvol (diethylstilbestrol) costs about $90 from a Canadian pharmacy.
DES, Lupron and side effects
Jacqueline Strax, whose husband succumbed to prostate cancer in 2001, recalls how PC-SPES had initially helped her husband. In 1984, her 44-year-old husband was told he had a month to live. He subsequently underwent orchiectomy (surgical removal of the testes) and the subsequent hormonal suppression was effective for many years. When the tumor later returned with a vengeance, he found PC-SPES on the internet, paid $10,000 to Sophie Chen after speaking with her on the telephone, and soon felt better. In 1998, he died of a hemorrhage. [PSA Rising, December 2003]
Was PC-SPES a killer or a life saver?
On September 5, 2004, the Washington Post ran a report with the headline: "Herbal remedies turn deadly for patients." How so? PC-SPES by all reports was prolonging life and saving men who were clinging to life. The Washington Post asserted the regulatory system of herbal product companies was flawed, claiming BotanicLab spiked its product with rat poison, the blood thinner that was eventually found in PC-SPES. The article called PC-SPES a "disaster," and reported 35 cases where users or their families claimed harm. These were men who were otherwise dying without hope.
The Washington Post article said: "Published studies showed that some of the men who took it (PC-SPES) got enlarged breasts, their nipples grew tender, their penises shrank, and they developed other problems." Yes, but they failed to report that these are the same side effects as are often experienced by those taking Lupron or other estrogen therapy drugs.
The Washington Post article said DES was tested for prostate cancer long ago, "but produced so many side effects, including blood clots, that most doctors concluded it would do more harm than good. It was largely discarded, but interest in it has cropped up from time to time because of scattered research showing it might work at low doses." Over 30 years ago doctors used 5 mg of DES. Today, lower doses are used.
PC-SPES was not intended to be used on men with early-stage prostate cancer. When hormone therapy doesn鈥檛 work any longer and the cancer continues to grow, the herbal treatment (PC-SPES) is "effective in those patients" said Dr. Aaron E. Katz. [LA Times, Oct. 21, 2000]
DES reconsidered
One outcome of the PC-SPES debacle is that physicians began to realize they had overlooked DES in favor of more expensive, but maybe not superior drugs, like Lupron. Thirty years ago 5 milligrams of DES was the standard dose prescribed, with considerable side effects noted. Today it is known that low-dose DES, 1 mg, is effective and produces fewer side effects.
Patrick Walsh, MD says that DES may be a more cost-effective agent in reducing PSA than other more aggressive regimens. [Journal Urology 173: 1966-68, 2005].
A more recent study showed that DES plus aspirin can produce a significant drop in PSA (23% experienced a more than 50% drop; 65% experienced a decline overall). [Urology International 75: 217-21, 2005]
DES, which reduces testosterone levels in the body by inhibiting luteinizing hormone in the pituitary gland, is still manufactured under the trade names Honvol (Baxter) and Stibestrol (Wellspring). It is also known to cause blood clots, reduced libido, and cause breast tenderness and related feminization in males. It is listed for primary use for the intensive and selective palliative therapy of inoperable prostate cancer. DES slows growth of tumor cells and may cause shrinkage of prostate tumors.
Back in the 1970s when diethylstilbestrol was being utilized with regularity among advanced-stage prostate cancer patients, here is what some of the reports said:
"High-dose diethylstilbestrol can used effectively in cases of prostate cancer when standard doses of estrogen have failed." [Canadian Medical Association Journal 109: 697-99, 1973]
"Of the conventional chemotherapy drugs available, only diethylstilbestrol has been safe, effective (at least in relieving bone pain) and available for repeat courses of treatment." [Urology Clinics North America 2: 185-96, 1975]
In 15 patients with advanced prostate cancer receiving diethylstilbestrol, their disease remained stable without evidence of progression for an average of 25.6 weeks. "There were no complete remissions, and no significant side effects were seen." [Urology 8: 231-33, 1976]
"Diethylstilbestrol has shown effective symptomatic relief in patients with metastatic carcinoma of the prostate. Diethylstilbestrol is recommended in the treatment of advanced carcinoma of the prostate with soft tissue metastasis. It is safe and effective, and the tumor responses outweigh the side effects of the drug." [Urology 7: 598-601, 1976]
So why was PC-SPES being recalled for containing trivial doses of DES? Moreover, why weren鈥檛 oncologists and urologists prescribing low-dose DES more often for their patients with advanced prostate cancer?
Call for greater regulation
Regulatory agencies have been waiting for the opportunity to change public opinion regarding dietary supplements and turn all dietary supplements into high-priced drugs. The calls for greater regulation of the dietary supplement industry during the PC-SPES ordeal were deafening. In one report on PC-SPES, The Wall Street Journal said that "makers of supplements don鈥檛 have to adhere to as rigorous manufacturing requirements or submit results of clinical trials to the FDA." [WSJ May 26, 2002] However, current laws require dietary supplements to be pure and contain only the ingredients listed on the label, which PC-SPES failed to do. No new regulations were needed to force BotanicLab to recall PC-SPES.
The journal CA, A Cancer Journal For Clinicians, said "natural products such as PC-SPES should be subject to the same standards and approaches as substances that are classified as pharmaceuticals. And for any anticancer modality to be considered for clinical use, it must compare favorably against a proven therapy in comparable groups of patients." [CA Cancer Journal Clinicians 51: 199-204, 2001] That鈥檚 exactly what PC-SPES demonstrated, in both animal and human studies.
The CA Journal report tabulated the results from four published studies and found 83% of males who took PC-SPES with advanced prostate cancer experienced greater than a 50% drop in their PSA levels. The report acknowledged that advanced prostate cancer patients have "limited options," noted that most investigators characterized the side effects associated with PC-SPES "as mild," and added that men on estrogen hormone therapy experienced similar side effects. The blood-clotting problems that arose later were the most serious side effects. Dr. Aaron E. Katz, of Columbia University College of Physicians %26amp; Surgeons said 2 to 4 % of PC-SPES users run the risk of blood clots, which is a potentially fatal problem. [Los Angeles Times, Oct. 21, 2000]
The report in CA Journal stated, that since the herbal formula had not undergone as rigorous studies as would pharmaceuticals, "physicians and patients must take the place of the agency that provides oversight for the regulated pharmaceuticals."
The FDA can ban supplements, but to do so it has to show "a significant or unreasonable risk of illness or injury." For men who were at the end of their rope, PC-SPES posed no greater risk than many approved drugs, namely DES or Lupron. The herbal products industry was brought to task for poor-quality products and cries for greater regulation are still being heard.
Conclusions
What can be concluded from the saga of PC-SPES? Who was responsible for spiking the dietary supplement? Why did drug molecules need to be added when PC-SPES appeared to work well without them? Why was the product recalled, actually taken out of the hands of patients with advanced prostate cancer, when it was by all reports working better than existing drugs and had similar side effect profiles?
The National Center for Complementary and Alternative Medicine, which was ready to sponsor a multi-million dollar study of PC-SPES before the accusations were raised, says it is "interested in resuming studies of PC-SPES with patients and funding new laboratory studies, but can only do so when a fully characterized and standardized, contaminant-free product using the original formulation becomes available." [NCCAM Publication No. D149, September 2002]
When BotanicLab conducted studies of its products, certainly any variances in the potency of active ingredients should have been apparent. Herbs can vary in the content of active ingredients, but herbal extracts can be standardized for a certain minimum percentage of the primary active ingredient. Why didn鈥檛 BotanicLab do this?
The chances of a product like PC-SPES returning to the marketplace with patients and attorneys ready to sue, and regulatory agencies ready to pounce, is nil.
PC-SPES was being asked to demonstrate absolute safety 鈥?no side effects, a standard that drugs with all their testing can鈥檛 achieve.
For comparison, regulated pharmaceutical drugs cause over 100,000 needless deaths annually from side effects caused by their proper use drugs and Public Citizen warns there are 181 unsafe or ineffective prescription drugs on the market. The Vioxx scandal only served to reveal that the FDA approves relatively unsafe drugs that increase mortality rates. The flawed regulatory model should not be used for dietary supplements.
Was there magic inside?
Scientific investigation of PC-SPES continues to this day, with batches of the product still under scrutiny. Researchers at the Keck Science Center in Clarement, California, tested PC-SPES from batches produced in 1998 and 2001. [Cancer Letters 220: 171-75, 2005]
PC-SPES and DES were tested in lab dishes with lung cancer cells. PC-SPES was effective even in cells that had developed resistance against chemotherapy drugs. PC-SPES both killed cancer cells and interrupted their normal immortal state to cause them to naturally die off (apoptosis), whereas none of the contaminants in PC-SPES (warfarin, DES or indomethacin) induced apoptosis.
Both batches of PC-SPES, even though they varied in the amount of contaminants, were equally effective against this non-sex hormone type of tumor cell. Even adding more DES, indomethacin and warfarin to the less contaminated PC-SPES samples did not increase its effectiveness.
Researchers conclude that "natural components in the herbal extract were responsible for the cancer cell destructiveness of PC-SPES." PC-SPES also inhibited detoxifying enzymes (cytochrome p450) that are involved in cancer drug resistance. This may have played a part in its unusual effectiveness against drug-resistant strains of tumor cells. [Cancer Letters 220: 171-75, 2005]
Was there some magic synergism in the array of eight botanical herbs in PC-SPES? By examination of the data, this appears to be so.
Dr. Fulton L. Saier, a physician and prostate cancer patient, said the recall of PC-SPES "will potentially cause the death of thousands of men." [Wall Street Journal, May 26, 2002]
Dr. William Oh said "the worst part (of the PC-SPES saga) was that PC-SPES was a very effective treatment with minimal toxicity for advanced cancer patients. These men don鈥檛 have many choices for therapy."
Dr. Sophie Chen added: "I feel the patients who had used PC-SPES are the victims of the whole thing."
So, in summary, what we have here is multi-herbal dietary supplement......
...whose individual ingredients are commonly sold without noticeable side effects
...that was "contaminated" with small amounts of FDA-approved drugs (DES, ibuprofen, warfarin)
...whose effectiveness was not attributed to minute quantities of drug molecules
...which worked better than the sum of its parts
...which exceeded the effectiveness of existing drug therapies for men with advanced prostate cancer
...and had similar side effect ratios to hormone treatment (Lupron, DES, estrogen)
鈥hose manufacturer somehow was implicated in covering up the side effects by spiking the product with drugs
... and whose manufacturer and even agencies that funded research studies, were sued by its users and their families
...because its ingredients were "undeclared" on the label and therefore, "could cause serious health effects if not taken under medical supervision"
...however, in most instances, was being prescribed by doctors
...and was therefore recalled by the FDA
Desperate men, for whom hormone therapy had failed, were then asked to return bottles of PC-SPES, thus condemning themselves to an inevitable fate.
The FDA recalled a valid cure for cancer because it was mislabeled, not because it was ineffective. The FDA enforced a product recall that doomed men to their certain early demise. Instead of allowing PC-SPES to remain on the market for compassionate reasons and working with doctors to minimize side effects, as they do with Lupron, the FDA banned PC-SPES.
November 7, 2007
Bill Sardi [send him mail] is author of the new book: You Don鈥檛 Have To Be Afraid Of Cancer Anymore.
Reply:yea man you need to go to a blog or something no one is going to read that whole thing on yahoo answers.
Reply:DES is not a popular drug because of its side effects. It has not been made in the U.S. since 1997 when Eli Lily stopped its manufacture due to lack of sales. In pregnant women, it is a tetragen. It makes their daughters sterile and at an increase risk for cancer, and it makes their sons have a higher risk for cancer. DES was approved for advanced prostate cancer and breast cancer therapy for post-menopausal women.
Indomethacin (NSAID) and warfarin (blood thinner) are approved prescription medications in the U.S.
Herbal medications are not allowed to make any claims of cure. As soon as they do, it becomes a drug. They then have to go through the new drug trial process to prove the claim.
The FDA normally fast tracks promising cancer drugs.
by Bill Sardi
by Bill Sardi
DIGG THIS
Excerpt from the book: You Don鈥檛 Have To Be Afraid Of Cancer Any More, by Bill Sardi 漏 2007
The most significant event in the recent history of prostate cancer care has been the introduction, for a time, of a combination herbal remedy that caught cancer doctors by surprise. This herbal dietary supplement captured the attention of prostate cancer patients and doctors alike. The herbal combo began extending the lives of otherwise helpless prostate cancer patients facing the advanced life-threatening form of their disease. How the cancer industry responded to this development, and the events surrounding the decision to withdraw this herbal formula from the marketplace, despite its unprecedented effectiveness, reveals much about the dismal state of cancer care in America. One cannot read this account without becoming outraged at the final outcome.
An herbal remedy captivates
About 230,000 men learn of their prostate cancer each year in the United States. Among them is a group of about 40,000 men who face the aggressive form of the disease where the cancer has begun to spread to bone and other organs, threatening their lives.
In the mid-1990s, men with this progressive form of prostate cancer found a multi-herbal remedy to be quite effective in subduing the pain, inflammation and spread of prostate cancer. Sadly, the product was suddenly recalled for mislabeling problems, never to be re-introduced.
The whole unfortunate tale is indicative of what is going on in the cancer care industry today and worthy of re-analysis here. This is a story that every male with prostate cancer needs to read and understand. If you are familiar with this story, new data places a different ending to the story.
The saga begins
Long about 1996, a research scientist by the name of Sophie Chen, PhD, a graduate of Columbia University and post-doctoral fellow at Cornell University, who spent 14 years working for pharmaceutical companies (Merck Sharp %26amp; Dohme and Bayer USA), developed a multi-herbal product for males with advanced prostate cancer. It was named PC-SPES. The PC stood for prostate cancer, and "spes" is the Latin word for hope.
In 1988, Dr. Chen began her research into the role that natural herbs can play in healing and curing cancer, and obtained a dozen U.S. patents. In 1993, Dr. Chen co-founded the International Medical Research Corporation with "Allan" Xuhui Wang, MD, and John Chen (her brother), which did business under the name BotanicLab, the maker of PC-SPES.
Chen and Wang, who is also an herbalist, collaborated to modify an existing herbal formula used in China to treat urologic problems, which became the PC-SPES product. The first patient to use it was Chen鈥檚 brother-in-law, a physician in Taiwan with advanced prostate cancer who was alive and well 10 years later. [Journal National Cancer Institute 94: 1266-68, 2002]
Over time Dr. Chen had secured research grants from the National Cancer Institute and prostate cancer survivor/investor Michael Milken鈥檚 CaP CURE organization. Eventually an $8 million study grant from the National Institutes of Health was obtained, but the study never took place due to product quality problems. [PSA Rising, Dec. 19, 2003]
Many urologists and oncologists believed the herbal mix was prolonging their patients鈥?lives. Over 100 studies were published, validating its beneficial effects.
PC-SPES got spiked
A report published in the Journal of the National Cancer Institute in 2002 said: "PC-SPES was poised to become the first cancer treatment to emerge from the realm of alternative medicine, pass rigorous clinical testing, and add a powerful natural weapon to the oncologist鈥檚 arsenal."
As positive as the reports were for PC-SPES, there were nagging reports of side effects. Doctors began to suspect that the side effects caused by PC-SPES were similar to those produced by diethylstilbestrol (DES), a testosterone inhibitor that has been used to treat prostate cancer for decades.
The spiking of PC-SPES with drug molecules wasn鈥檛 apparent at first. A study published in 1998 found estrogen-like effects, but couldn鈥檛 identify the molecule involved. The study didn鈥檛 find any DES in PC-SPES at that time. [New England Journal Medicine 339: 785-91, Sept. 17, 1998] Chen denied the presence of any ingredients not on the label. Three times the California FDA tested PC-SPES and found no contamination, but utilized testing methods that could not detect minute amounts.
Then, as reports of side effects began to accumulate in 2001, some men suddenly noticed PC-SPES stopped working for them. PSA levels started to rise. Also a few cases of hemorrhaging were reported. Trace amounts of a blood thinner (warfarin) had been added to subsequent batches of PC-SPES in an apparent effort to counter reported blood clots.
It was later found that some batches of PC-SPES given to men in a comparative study contained from 0.01 to 3.1 % of DES. [Canadian Journal Urology 9: 1684-88, 2002] However, this wasn鈥檛 considered to be sufficient to cause the side effects being reported, in particular, the reports of blood clots.
Patients take charge
Cancer patients were communicating with each other via the internet, learning of the rising PSA levels among PC-SPES users.
Susan Domizi, wife of a Connecticut man taking PC-SPES, sent samples of the product to a laboratory and found it contained small amounts of DES. A second study also found DES. [International Journal Oncology 20: 583-88, 2002] By October of 2001, doctors had published a case of severe hemorrhaging associated with PC-SPES that was aired in the New England Journal of Medicine. [New England Journal Medicine 345: 1213-14, 2001]
Then the State of California FDA returned to BotanicLab to conduct more sensitive tests and surprisingly found DES in the same lots they had tested before, as well as the presence of another drug, warfarin (coumadin), a blood thinner. Retrospective tests now showed the product had been spiked with DES since 1996, and when side effects were reported, subsequent batches of PC-SPES displayed lower doses of DES, and then eventually the blood thinner, as if someone was attempting to limit the side effects. Sophie Chen responded by saying that none of the drugs was present in therapeutic doses and that "lots without DES worked equally well."
The eight herbs in PC-SPES
The Added Drug Ingredients
Licorice root
Reishi mushroom
Chrysanthemum
Dyers woad
Rabdosia
Saw palmetto
Baikal skullcap
Ginseng
Diethylstibestrol (DES) (testosterone interruptor)
Indomethacin (anti-inflammatory)
Warfarin (blood thinner)
Breakthrough in process
Whatever ingredients were in PC-SPES, they were producing a breakthrough in prostate cancer treatment all the while the product was being slammed for adulteration.
Michael Cook is an example. A 49-year-old who was diagnosed with prostate cancer at age 44, his tumors had spread to his ribs and pelvis. PC-SPES dropped his PSA from 80 to 0.2. "I鈥檝e been on PC-SPES for three years now, and I seem to be in complete remission," said the patient. [LA Times Oct. 21, 2000]
A group of men with prostate cancer, called UsToo, reported that their members maintained a low PSA concentration with PC-SPES in two successive surveys (88% and 93%). "Even though there were some side effects, a great majority of men are realizing good PSA control while taking the capsules, with some users now into their fourth year of PC-SPES use," said their report. [Molecular Urology 4: 289-91, 2000]
Moreover, a study conducted by Eric Small, MD and William Oh, MD at the University of California at San Francisco, showed that PC-SPES produced a 47% response rate compared to just 28% for diethylstiberstrol alone, and reduced PSA levels by more than 80% in all of their prostate cancer patients, with one patient experiencing complete disappearance of a bladder mass. In Dr. Small and Oh鈥檚 study involving 37 patients, three experienced blood clots. Side effects, however, were deemed to be "acceptable." [Journal Clinical Oncology 18: 3595-3603, 2000; Urology 57: 122-26, 2001]
A report in the Journal of Urology stated the side effect profile of PC-SPES was "comparable to estrogen treatment," with 42% experiencing nipple tenderness, 8% breast enlargement and 7% hot flashes. [Journal Urology 164: 1229-34, 2000]
Dr. Charles Myers of the American Institute for Diseases of the Prostate, in Charlottesville, Virginia, reported the case of a man whose PSA was nearly 3,000, an alarming level, but after taking PC-SPES it fell rapidly to below 1. Dr. Myers called PC-SPES "probably the most active agent" for treating prostate cancer in patients who no longer get results from conventional, hormone-blocking drugs. [Wall Street Journal May 26, 2002]
Still a mystery
Since no proof existed to show that BotanicLab had purchased any of these drug molecules, the blame for adulteration was cast upon sources of the herbs in China. Chen stated that she was not personally involved in mixing the company鈥檚 products, saying she was in New York conducting research most of the time, not in their Brea, California headquarters.
But Chen also contradicted herself when she said she had tested the herbal products herself and they were pure prior to encapsulation. She claimed the alcohol extraction of the herbs was conducted by companies in China, not in the United States. One of those suppliers in China also processed pharmaceuticals and could have been to blame. But they would have had to know what was going on in the United States to alter the product as they did.
Strangely, the Washington Post report stated that BotanicLab had conducted tests on its own in 2002 and determined bulk herbs coming into the country were free of pharmaceuticals, while packaged products leaving the Brea facility were adulterated. The Washington Post report said: "Tests conducted after BotanicLab shut down showed changes in pharmaceutical ingredients over time that the people suing BotanicLab regard as evidence of a conscious effort to manage troublesome side effects."
Blood clots are common in cancer patients, so this problem may not be attributed to PC-SPES. [Medicine 56: 1-37, 1977] But the addition of the anti-clotting drug warfarin, and the cases of hemorrhage, were certainly a concern.
The penalties
It took five years to shut down BotanicLab. PC-SPES was voluntarily recalled in 2002. Under agreements, John Chen, sister Sophie Chen, and Allan Xuhui Wang admitted to single misdemeanors involving the marketing of misbranded and adulterated food. Their defunct company pleaded no contest to the felony count of producing a product that presents a danger to the public. The corporation agreed to pay $350,000, the Chen鈥檚 agreed to pay $46,500 each, and Wang agreed to pay $56,500. Cancer survivors who had used PC SPES filed a class-action lawsuit against BotanicLab.
Patients sue
Later patients even sued the Milken Prostate Cancer Foundation. "Giving people prescription drugs without their knowledge is insane. It is total fraud," a woman was quoted as saying in a Washington Post article. [Washington Post, Sept. 5, 2004]
What caused the beneficial effects?
In 2000, researchers at Columbia University reported that "estrogen-like activity is not its [PC-SPES鈥橾 sole mechanism of action." [Journal Urology 164: 1229-34, 2000]
Investigators at New York Medical College obtained samples of single herb extracts used in the PC-SPES product and determined that no single herb could exert the reductions in PSA and testosterone reported in other studies. The authors of that study said "PC-SPES should be considered a single function unit since the combination of its biological properties appears to be more effective than its individual components." [International Journal Oncology 20: 583-88, 2002]
Dr. Oh stated there was something else in PC-SPES causing the beneficial results. Another study found that men taking nine PC-SPES capsules a day could get as much as 0.5 mg of DES per day, compared to the 3.0 mg used in the comparative study of the two drugs. So it appeared a small amount of DES was being added intentionally without being identified on the product label.
The cost
About 10,000 men in advanced stages of prostate cancer were estimated to be taking 6-9 capsules of PC-SPES per day at a retail cost ranging from $400 to $500 per month. An attorney estimated BotanicLab may have taken in $50 million before it was shut down.
For comparison, Canadian pharmacies are selling Lupron kits for $325-486. Lupron stops production of testosterone by the testes. Side effects with Lupron include breast enlargement and decreased libido, similar to those produced by PC-SPES. Over $876 million of Lupron was sold in 2004. Yet one physician, Glenn Bubley, MD, of Harvard Medical School was quoted as saying the manufacturer of PC-SPES "is making more money than God." [WebMD August 31, 2000] Another comparison: a 10-milliliter dose of Honvol (diethylstilbestrol) costs about $90 from a Canadian pharmacy.
DES, Lupron and side effects
Jacqueline Strax, whose husband succumbed to prostate cancer in 2001, recalls how PC-SPES had initially helped her husband. In 1984, her 44-year-old husband was told he had a month to live. He subsequently underwent orchiectomy (surgical removal of the testes) and the subsequent hormonal suppression was effective for many years. When the tumor later returned with a vengeance, he found PC-SPES on the internet, paid $10,000 to Sophie Chen after speaking with her on the telephone, and soon felt better. In 1998, he died of a hemorrhage. [PSA Rising, December 2003]
Was PC-SPES a killer or a life saver?
On September 5, 2004, the Washington Post ran a report with the headline: "Herbal remedies turn deadly for patients." How so? PC-SPES by all reports was prolonging life and saving men who were clinging to life. The Washington Post asserted the regulatory system of herbal product companies was flawed, claiming BotanicLab spiked its product with rat poison, the blood thinner that was eventually found in PC-SPES. The article called PC-SPES a "disaster," and reported 35 cases where users or their families claimed harm. These were men who were otherwise dying without hope.
The Washington Post article said: "Published studies showed that some of the men who took it (PC-SPES) got enlarged breasts, their nipples grew tender, their penises shrank, and they developed other problems." Yes, but they failed to report that these are the same side effects as are often experienced by those taking Lupron or other estrogen therapy drugs.
The Washington Post article said DES was tested for prostate cancer long ago, "but produced so many side effects, including blood clots, that most doctors concluded it would do more harm than good. It was largely discarded, but interest in it has cropped up from time to time because of scattered research showing it might work at low doses." Over 30 years ago doctors used 5 mg of DES. Today, lower doses are used.
PC-SPES was not intended to be used on men with early-stage prostate cancer. When hormone therapy doesn鈥檛 work any longer and the cancer continues to grow, the herbal treatment (PC-SPES) is "effective in those patients" said Dr. Aaron E. Katz. [LA Times, Oct. 21, 2000]
DES reconsidered
One outcome of the PC-SPES debacle is that physicians began to realize they had overlooked DES in favor of more expensive, but maybe not superior drugs, like Lupron. Thirty years ago 5 milligrams of DES was the standard dose prescribed, with considerable side effects noted. Today it is known that low-dose DES, 1 mg, is effective and produces fewer side effects.
Patrick Walsh, MD says that DES may be a more cost-effective agent in reducing PSA than other more aggressive regimens. [Journal Urology 173: 1966-68, 2005].
A more recent study showed that DES plus aspirin can produce a significant drop in PSA (23% experienced a more than 50% drop; 65% experienced a decline overall). [Urology International 75: 217-21, 2005]
DES, which reduces testosterone levels in the body by inhibiting luteinizing hormone in the pituitary gland, is still manufactured under the trade names Honvol (Baxter) and Stibestrol (Wellspring). It is also known to cause blood clots, reduced libido, and cause breast tenderness and related feminization in males. It is listed for primary use for the intensive and selective palliative therapy of inoperable prostate cancer. DES slows growth of tumor cells and may cause shrinkage of prostate tumors.
Back in the 1970s when diethylstilbestrol was being utilized with regularity among advanced-stage prostate cancer patients, here is what some of the reports said:
"High-dose diethylstilbestrol can used effectively in cases of prostate cancer when standard doses of estrogen have failed." [Canadian Medical Association Journal 109: 697-99, 1973]
"Of the conventional chemotherapy drugs available, only diethylstilbestrol has been safe, effective (at least in relieving bone pain) and available for repeat courses of treatment." [Urology Clinics North America 2: 185-96, 1975]
In 15 patients with advanced prostate cancer receiving diethylstilbestrol, their disease remained stable without evidence of progression for an average of 25.6 weeks. "There were no complete remissions, and no significant side effects were seen." [Urology 8: 231-33, 1976]
"Diethylstilbestrol has shown effective symptomatic relief in patients with metastatic carcinoma of the prostate. Diethylstilbestrol is recommended in the treatment of advanced carcinoma of the prostate with soft tissue metastasis. It is safe and effective, and the tumor responses outweigh the side effects of the drug." [Urology 7: 598-601, 1976]
So why was PC-SPES being recalled for containing trivial doses of DES? Moreover, why weren鈥檛 oncologists and urologists prescribing low-dose DES more often for their patients with advanced prostate cancer?
Call for greater regulation
Regulatory agencies have been waiting for the opportunity to change public opinion regarding dietary supplements and turn all dietary supplements into high-priced drugs. The calls for greater regulation of the dietary supplement industry during the PC-SPES ordeal were deafening. In one report on PC-SPES, The Wall Street Journal said that "makers of supplements don鈥檛 have to adhere to as rigorous manufacturing requirements or submit results of clinical trials to the FDA." [WSJ May 26, 2002] However, current laws require dietary supplements to be pure and contain only the ingredients listed on the label, which PC-SPES failed to do. No new regulations were needed to force BotanicLab to recall PC-SPES.
The journal CA, A Cancer Journal For Clinicians, said "natural products such as PC-SPES should be subject to the same standards and approaches as substances that are classified as pharmaceuticals. And for any anticancer modality to be considered for clinical use, it must compare favorably against a proven therapy in comparable groups of patients." [CA Cancer Journal Clinicians 51: 199-204, 2001] That鈥檚 exactly what PC-SPES demonstrated, in both animal and human studies.
The CA Journal report tabulated the results from four published studies and found 83% of males who took PC-SPES with advanced prostate cancer experienced greater than a 50% drop in their PSA levels. The report acknowledged that advanced prostate cancer patients have "limited options," noted that most investigators characterized the side effects associated with PC-SPES "as mild," and added that men on estrogen hormone therapy experienced similar side effects. The blood-clotting problems that arose later were the most serious side effects. Dr. Aaron E. Katz, of Columbia University College of Physicians %26amp; Surgeons said 2 to 4 % of PC-SPES users run the risk of blood clots, which is a potentially fatal problem. [Los Angeles Times, Oct. 21, 2000]
The report in CA Journal stated, that since the herbal formula had not undergone as rigorous studies as would pharmaceuticals, "physicians and patients must take the place of the agency that provides oversight for the regulated pharmaceuticals."
The FDA can ban supplements, but to do so it has to show "a significant or unreasonable risk of illness or injury." For men who were at the end of their rope, PC-SPES posed no greater risk than many approved drugs, namely DES or Lupron. The herbal products industry was brought to task for poor-quality products and cries for greater regulation are still being heard.
Conclusions
What can be concluded from the saga of PC-SPES? Who was responsible for spiking the dietary supplement? Why did drug molecules need to be added when PC-SPES appeared to work well without them? Why was the product recalled, actually taken out of the hands of patients with advanced prostate cancer, when it was by all reports working better than existing drugs and had similar side effect profiles?
The National Center for Complementary and Alternative Medicine, which was ready to sponsor a multi-million dollar study of PC-SPES before the accusations were raised, says it is "interested in resuming studies of PC-SPES with patients and funding new laboratory studies, but can only do so when a fully characterized and standardized, contaminant-free product using the original formulation becomes available." [NCCAM Publication No. D149, September 2002]
When BotanicLab conducted studies of its products, certainly any variances in the potency of active ingredients should have been apparent. Herbs can vary in the content of active ingredients, but herbal extracts can be standardized for a certain minimum percentage of the primary active ingredient. Why didn鈥檛 BotanicLab do this?
The chances of a product like PC-SPES returning to the marketplace with patients and attorneys ready to sue, and regulatory agencies ready to pounce, is nil.
PC-SPES was being asked to demonstrate absolute safety 鈥?no side effects, a standard that drugs with all their testing can鈥檛 achieve.
For comparison, regulated pharmaceutical drugs cause over 100,000 needless deaths annually from side effects caused by their proper use drugs and Public Citizen warns there are 181 unsafe or ineffective prescription drugs on the market. The Vioxx scandal only served to reveal that the FDA approves relatively unsafe drugs that increase mortality rates. The flawed regulatory model should not be used for dietary supplements.
Was there magic inside?
Scientific investigation of PC-SPES continues to this day, with batches of the product still under scrutiny. Researchers at the Keck Science Center in Clarement, California, tested PC-SPES from batches produced in 1998 and 2001. [Cancer Letters 220: 171-75, 2005]
PC-SPES and DES were tested in lab dishes with lung cancer cells. PC-SPES was effective even in cells that had developed resistance against chemotherapy drugs. PC-SPES both killed cancer cells and interrupted their normal immortal state to cause them to naturally die off (apoptosis), whereas none of the contaminants in PC-SPES (warfarin, DES or indomethacin) induced apoptosis.
Both batches of PC-SPES, even though they varied in the amount of contaminants, were equally effective against this non-sex hormone type of tumor cell. Even adding more DES, indomethacin and warfarin to the less contaminated PC-SPES samples did not increase its effectiveness.
Researchers conclude that "natural components in the herbal extract were responsible for the cancer cell destructiveness of PC-SPES." PC-SPES also inhibited detoxifying enzymes (cytochrome p450) that are involved in cancer drug resistance. This may have played a part in its unusual effectiveness against drug-resistant strains of tumor cells. [Cancer Letters 220: 171-75, 2005]
Was there some magic synergism in the array of eight botanical herbs in PC-SPES? By examination of the data, this appears to be so.
Dr. Fulton L. Saier, a physician and prostate cancer patient, said the recall of PC-SPES "will potentially cause the death of thousands of men." [Wall Street Journal, May 26, 2002]
Dr. William Oh said "the worst part (of the PC-SPES saga) was that PC-SPES was a very effective treatment with minimal toxicity for advanced cancer patients. These men don鈥檛 have many choices for therapy."
Dr. Sophie Chen added: "I feel the patients who had used PC-SPES are the victims of the whole thing."
So, in summary, what we have here is multi-herbal dietary supplement......
...whose individual ingredients are commonly sold without noticeable side effects
...that was "contaminated" with small amounts of FDA-approved drugs (DES, ibuprofen, warfarin)
...whose effectiveness was not attributed to minute quantities of drug molecules
...which worked better than the sum of its parts
...which exceeded the effectiveness of existing drug therapies for men with advanced prostate cancer
...and had similar side effect ratios to hormone treatment (Lupron, DES, estrogen)
鈥hose manufacturer somehow was implicated in covering up the side effects by spiking the product with drugs
... and whose manufacturer and even agencies that funded research studies, were sued by its users and their families
...because its ingredients were "undeclared" on the label and therefore, "could cause serious health effects if not taken under medical supervision"
...however, in most instances, was being prescribed by doctors
...and was therefore recalled by the FDA
Desperate men, for whom hormone therapy had failed, were then asked to return bottles of PC-SPES, thus condemning themselves to an inevitable fate.
The FDA recalled a valid cure for cancer because it was mislabeled, not because it was ineffective. The FDA enforced a product recall that doomed men to their certain early demise. Instead of allowing PC-SPES to remain on the market for compassionate reasons and working with doctors to minimize side effects, as they do with Lupron, the FDA banned PC-SPES.
November 7, 2007
Bill Sardi [send him mail] is author of the new book: You Don鈥檛 Have To Be Afraid Of Cancer Anymore.
Reply:yea man you need to go to a blog or something no one is going to read that whole thing on yahoo answers.
Reply:DES is not a popular drug because of its side effects. It has not been made in the U.S. since 1997 when Eli Lily stopped its manufacture due to lack of sales. In pregnant women, it is a tetragen. It makes their daughters sterile and at an increase risk for cancer, and it makes their sons have a higher risk for cancer. DES was approved for advanced prostate cancer and breast cancer therapy for post-menopausal women.
Indomethacin (NSAID) and warfarin (blood thinner) are approved prescription medications in the U.S.
Herbal medications are not allowed to make any claims of cure. As soon as they do, it becomes a drug. They then have to go through the new drug trial process to prove the claim.
The FDA normally fast tracks promising cancer drugs.
Can anti-perspirants and/or deoderants be harmful to my health?
96>Every now and then I hear reports of certain ingredients (aluminum oxide?) in anti-perspirants and deoderants that could be linked to cancer. How concerned should I be? Are there types of deoderants that are "safe"?
Reply:the story goes that the aluminium oxide enters the body through shaving nicks and can clog the lymph nodes, causing cancer. however the study that suggested this was a relatively small one and thin on evidence. others studies are researching further into it, but so far there has been no evidence that they are harmful
Reply:Not at all. If you don't use deodorant then THAT can be very harmful to your health.
Reply:I too have heard that the aluminum compounds are bad, and they can go right into your system thru your sweat glands, so I don't use deodorants. It is not a problem if you bathe every day.
Reply:My friend is allergic to that kind of stuff. So I think if you are allergic it may trigger cancer. But I have never ever heard that. I use secret and I have no idea what ingrediants it has. I just use it with no worries.
Just don't worry. I have learned that. I have HIV, my brother's in juvi, my mom was diagnosed with cancer. I have learned not to worry and that life is short so enjoy it while you have it.
God Bless!
Reply:Deodorants are okay but the anti-perspirants are not. They suppress the activity of our sweat glands, which is not normal.
Reply:I heard if you are a woman it can sontribute to breast cancer. But the % is probably so small. They do make an all natural deoderant and it doesn't really work
Reply:ive read that anti-perspirant are harmful because it prevents your underarm from discharging wastes(that's why underarm smells)...it just collects in there and evetually can lead to tumors or cancer...
Reply:Well there is a speculation - specially when you use the deo stick. What you can do is use the body sprey's or roll overs - any natural product would be the best recommended. Try Body Shop !
Reply:It's not true, but if you're still concerned about those ingredients try an all natural version. I like the Kiss My Face brand.
flower arrangements
Reply:the story goes that the aluminium oxide enters the body through shaving nicks and can clog the lymph nodes, causing cancer. however the study that suggested this was a relatively small one and thin on evidence. others studies are researching further into it, but so far there has been no evidence that they are harmful
Reply:Not at all. If you don't use deodorant then THAT can be very harmful to your health.
Reply:I too have heard that the aluminum compounds are bad, and they can go right into your system thru your sweat glands, so I don't use deodorants. It is not a problem if you bathe every day.
Reply:My friend is allergic to that kind of stuff. So I think if you are allergic it may trigger cancer. But I have never ever heard that. I use secret and I have no idea what ingrediants it has. I just use it with no worries.
Just don't worry. I have learned that. I have HIV, my brother's in juvi, my mom was diagnosed with cancer. I have learned not to worry and that life is short so enjoy it while you have it.
God Bless!
Reply:Deodorants are okay but the anti-perspirants are not. They suppress the activity of our sweat glands, which is not normal.
Reply:I heard if you are a woman it can sontribute to breast cancer. But the % is probably so small. They do make an all natural deoderant and it doesn't really work
Reply:ive read that anti-perspirant are harmful because it prevents your underarm from discharging wastes(that's why underarm smells)...it just collects in there and evetually can lead to tumors or cancer...
Reply:Well there is a speculation - specially when you use the deo stick. What you can do is use the body sprey's or roll overs - any natural product would be the best recommended. Try Body Shop !
Reply:It's not true, but if you're still concerned about those ingredients try an all natural version. I like the Kiss My Face brand.
flower arrangements
How bad is bone cancer?
95>My dad was diagnosed a few months ago with prostate cancer. They've been treating him with some anti-testosterone shot and it seems to be working. His blood work shows an dramatic improvement in the 3-4 months since that started. But, he was told that although it hadn't spread to any of his organs that it had "affected his bones." He's been having a lot of difficulty and pain that has gotten worse and is going to see an oncologist in a week and a half. He isn't sure that he has bone cancer, but he's pretty sure that was what the doctor meant.
So, while I know that the prognosis for prostate cancer is quite good and that there is an excellent recovery rate for that I know very little about bone cancer. I have the impression that it is much more serious. Is it a pretty fatal disease? How treatable is it???
Reply:have you ever heard of mastasis well it means the cancer has gone to a certain part of the body. I dont know your dad but god does I will pray for him.
Just wait til you see the dr.
Reply:Bone cancer just keeps spreading. I urge you to read up on an herbal combination called "Essiac" that, according to many websites, have cured people of their cancer. The use of herbs once was mainstream medicine but, because there is no great profit to be made from these unpatentable wonder drugs, they have lost their status as mainstream therapies.
Please don't think this is a bunch of malarky. You owe it to your dad and your family to at least read about it.
http://www.bccancer.bc.ca/HPI/Unconventi...
http://curezone.com/blogs/m.asp?f=10%26amp;i=3
http://www.healthfreedom.info/Cancer%20E...
http://www.shirleys-wellness-cafe.com/ca...
http://www.medical-library.net/sites/fra...
http://www.alternative-cancer.net/?hop=0
Reply:talking about cancers,well we all knew that it is a number one man killer disease,so it means it is so bad because a man having this kind of disease will really suffer.
Reply:If the oncologist knew that the cancer had affected his bones, then I will assume that he can run the same tests again and see if there is any change in the bones. Yes, I would consider bone cancer more difficult in general then prostate cancer, but you are not really worried about in general, you are worried about your dad. General answers may not apply.
Will your dad let you go with him to the doctors visit? It is sometimes better if two people hear what the doctor says and have a chance to ask questions, rather then ask your dad for answers that he didn't ask for. Good luck.
Reply:my mom had small cell lung cancer that metastized and spread to her bones. She passed away about a year ago. There was nothing that could be done for her, she was completely cover from head to toe. Good luck, and i'm sorry to hear.
Reply:My husband was treated with radiation it helped with the pain. His cancer was everywhere. The radiation shrunk the tumor on his spine but it is very hard on bone marrow Good luck and God Bless
So, while I know that the prognosis for prostate cancer is quite good and that there is an excellent recovery rate for that I know very little about bone cancer. I have the impression that it is much more serious. Is it a pretty fatal disease? How treatable is it???
Reply:have you ever heard of mastasis well it means the cancer has gone to a certain part of the body. I dont know your dad but god does I will pray for him.
Just wait til you see the dr.
Reply:Bone cancer just keeps spreading. I urge you to read up on an herbal combination called "Essiac" that, according to many websites, have cured people of their cancer. The use of herbs once was mainstream medicine but, because there is no great profit to be made from these unpatentable wonder drugs, they have lost their status as mainstream therapies.
Please don't think this is a bunch of malarky. You owe it to your dad and your family to at least read about it.
http://www.bccancer.bc.ca/HPI/Unconventi...
http://curezone.com/blogs/m.asp?f=10%26amp;i=3
http://www.healthfreedom.info/Cancer%20E...
http://www.shirleys-wellness-cafe.com/ca...
http://www.medical-library.net/sites/fra...
http://www.alternative-cancer.net/?hop=0
Reply:talking about cancers,well we all knew that it is a number one man killer disease,so it means it is so bad because a man having this kind of disease will really suffer.
Reply:If the oncologist knew that the cancer had affected his bones, then I will assume that he can run the same tests again and see if there is any change in the bones. Yes, I would consider bone cancer more difficult in general then prostate cancer, but you are not really worried about in general, you are worried about your dad. General answers may not apply.
Will your dad let you go with him to the doctors visit? It is sometimes better if two people hear what the doctor says and have a chance to ask questions, rather then ask your dad for answers that he didn't ask for. Good luck.
Reply:my mom had small cell lung cancer that metastized and spread to her bones. She passed away about a year ago. There was nothing that could be done for her, she was completely cover from head to toe. Good luck, and i'm sorry to hear.
Reply:My husband was treated with radiation it helped with the pain. His cancer was everywhere. The radiation shrunk the tumor on his spine but it is very hard on bone marrow Good luck and God Bless
Just how special are anti-oxidents?
94>i drink green tea pretty much everyday, apparently its a source of "natural anti oxidents"... how helpful are they in preventing cancer? as so i have heard..
Reply:No one knows because people who drink green tea every day still can get cancer. There are over 200 different types of cancer and so far there is no known way to prevent the occurence of every single one of them. What drinking green tea might do is lessen the risk of developing one kind of cancer only . . but than you would contend with the other 199 types. So, just drinking green tea may or may not be helpful . . if you enjoy drinking it, by all means continue, but do not operate under the false security that by drinking tea or focusing on 'natural anit-oxidants' that you will be safe from ever getting cancer. People who have never smoked, don't drink, eat nutrious, watch their weight, have special diets . . all still can get cancer. There is no fool proof way to stop every single kind of cancer . . if there was . . than we'd all use it. I know a young man who believed that changing his diet was essential to stopping his cancer. He had surgery to remove a single 2cm tumor and than refused tradional adjuvant chemotherapy. Instead he concentrated on a naturalistic diet and ate only veggies. He did this for six months and was stunned at his last doctors visit to learn that during that six month period of eating and living healthy . . his cancer was back and had metastasized throughout the body. His response was that he now realizes that diet alone cannot stop the growth and spred of cancer . . but diet can make you feel healthier and better able to fight the cancer should you ever get it. He is now doing tradional chemo and had a 50 percent response in the past few months. So . . what does this mean? Bascially that a healthy diet can keep you fit so that you can fight cancer better . . but it won't stop the progession and spred of disease.
Drink your green tea . . but, unfortunately, you can still get cancer no matter how much of it you drink.
Reply:their very helpful in preventing cancer as a part of a over all healthy lifestyle. actually their essential for it. well that's what they say anyway.
the red apples have got a good one too, in the skin. and then you get some pectin as well that helps remove excess cholesterol from your body. so their a extremely healthy snack.
Reply:No one knows because people who drink green tea every day still can get cancer. There are over 200 different types of cancer and so far there is no known way to prevent the occurence of every single one of them. What drinking green tea might do is lessen the risk of developing one kind of cancer only . . but than you would contend with the other 199 types. So, just drinking green tea may or may not be helpful . . if you enjoy drinking it, by all means continue, but do not operate under the false security that by drinking tea or focusing on 'natural anit-oxidants' that you will be safe from ever getting cancer. People who have never smoked, don't drink, eat nutrious, watch their weight, have special diets . . all still can get cancer. There is no fool proof way to stop every single kind of cancer . . if there was . . than we'd all use it. I know a young man who believed that changing his diet was essential to stopping his cancer. He had surgery to remove a single 2cm tumor and than refused tradional adjuvant chemotherapy. Instead he concentrated on a naturalistic diet and ate only veggies. He did this for six months and was stunned at his last doctors visit to learn that during that six month period of eating and living healthy . . his cancer was back and had metastasized throughout the body. His response was that he now realizes that diet alone cannot stop the growth and spred of cancer . . but diet can make you feel healthier and better able to fight the cancer should you ever get it. He is now doing tradional chemo and had a 50 percent response in the past few months. So . . what does this mean? Bascially that a healthy diet can keep you fit so that you can fight cancer better . . but it won't stop the progession and spred of disease.
Drink your green tea . . but, unfortunately, you can still get cancer no matter how much of it you drink.
Reply:their very helpful in preventing cancer as a part of a over all healthy lifestyle. actually their essential for it. well that's what they say anyway.
the red apples have got a good one too, in the skin. and then you get some pectin as well that helps remove excess cholesterol from your body. so their a extremely healthy snack.
What are the pros and cons of medicating cancer patients for depression?
93>Basically, I'm wondering if other cancer patients have benefitted from taking anti-depression drugs. I think I've managed fairly well so far but lately I've been feeling in the depths od despair, usually at the same time each month so I think the hormones are messing with my emotions. I've been dealing with breast cancer for 2 1/2 years now and am at stage IV and in maintenance mode, managing the mets which will probably be with me for the rest of my hopefully long life.銆€ Could the Herceptin I get weekly be a factor or is it just a case of being tired of dealing with it plus hormones pushing me so close to the edge every month? I will ask my oncologist about possible medication to keep the blues away. I'd appreciate comments and advice on what to expect.
Reply:I know what you are talking about. I was diagnosed 3 years ago with breast cancer and it wasn't until about 8 months ago that I started taking an anti-depressant on a regular basis. I made myself a promise that I would continue them for a year and see where I am at. They have helped me so much! I used to have some scary thoughts, but they have gone away. I finally figured out that I deserve to feel better and the only way I could do it was with the help of meds. I am glad I made that choice. Yeah, there are days that suck, but there are more days that I am able to smile and mean it. Good luck, and take care.
Reply:For depression the best medicine is laughter. Read jokes, see comedies and talk jovially with everybody. Go out and enjoy nature, animals and birds. Visit parks and watch trees and animals which do not have any mental problems since they do not think like us.
Think always positive. Thinking only brought all problems man is facing now including the global warming.
Reply:Get some Xanax it will take off a lot of stress
Reply:There are only pros and very few cons. So they should be used more frequently. They may not help as depression is often situational so treating cancer and its cure is usually needed to help depression.
Reply:I hope You get well soon.. I'm doing my best to help every1 to cure their illness including you.. with my Islam Prayers.. You don`t have to vote me for the best answer.. im doing this for free.. I only hopping we all get bless %26amp; Cure from Allah the most Mercyfull..%26amp; Most Loving.. See the improvement result..
I Wish Your doctor show You a Good resault.. from Your condiction %26amp; situation.. as Fast as Posible..
Reply:I know what you are talking about. I was diagnosed 3 years ago with breast cancer and it wasn't until about 8 months ago that I started taking an anti-depressant on a regular basis. I made myself a promise that I would continue them for a year and see where I am at. They have helped me so much! I used to have some scary thoughts, but they have gone away. I finally figured out that I deserve to feel better and the only way I could do it was with the help of meds. I am glad I made that choice. Yeah, there are days that suck, but there are more days that I am able to smile and mean it. Good luck, and take care.
Reply:For depression the best medicine is laughter. Read jokes, see comedies and talk jovially with everybody. Go out and enjoy nature, animals and birds. Visit parks and watch trees and animals which do not have any mental problems since they do not think like us.
Think always positive. Thinking only brought all problems man is facing now including the global warming.
Reply:Get some Xanax it will take off a lot of stress
Reply:There are only pros and very few cons. So they should be used more frequently. They may not help as depression is often situational so treating cancer and its cure is usually needed to help depression.
Reply:I hope You get well soon.. I'm doing my best to help every1 to cure their illness including you.. with my Islam Prayers.. You don`t have to vote me for the best answer.. im doing this for free.. I only hopping we all get bless %26amp; Cure from Allah the most Mercyfull..%26amp; Most Loving.. See the improvement result..
I Wish Your doctor show You a Good resault.. from Your condiction %26amp; situation.. as Fast as Posible..
Do anti-inflammatories cover up bone pain symptoms of leukemia?
92>My sister is undergoing a biposy tomorrow to see if she has cancer.
She's had bone pain in her arm for over one year now. One doctor diagnosed it as an arthritic joint in late 2005. Another put her on anti-inflammatories and physical therapy for bursitis/frozen shoulder in October of 2006. The drugs alleviated the bone pain a little bit but the shoulder joint and back and spine remained very achey. She looked uncomfortable and pale all of the time and I kept telling her that maybe she should see another doctor.
She finally went to a different doctor last week when she noticed some swollen lymph nodes in her neck. Her blood tests revealed that she's very anemic.
Do anti-inflammatories delay a correct diagnisis of cancer by masking/reducing bone pain? She's been looking unwell for a long time and unfortunately, her doctors only viewed her as a body part (in this case a shoulder) instead of a whole person who looked quite obviously, unwell. I'm just terribly worried about her
Reply:Lots of things can delay a correct diagnosis of cancer. Anti-inflammatory drugs or pain pills can mask pain but you would still have fever, weight loss or fatigue that would not be easily masked by anti-inflammatory medication.
Yes, the Dr should have looked at her as a whole person. Does she have an internist she sees at least once or twice a year that would have done blood work and noticed her declining health? If she is over thirty or so then she needs to see a Dr yearly at a minimum even if she isn't ill. When someone who doesn't see a Dr regularly comes in with a complaint about shoulder pain then the Dr treats the shoulder pain and cancer would not be their first thought.
From the symptoms you mentioned cancer is still just one possibility of a number of possible health problems so don't start assuming that this means she has cancer. There are a number of non cancer possibilities that need to be eliminated from consideration before she will have a diagnosis.
If your sister does turn out to have cancer my suggestion is to help your sister deal with her illness, be there for her, and help her remain positive each and every day. Don't waste time with the "what ifs" because it doesn't help you or her. good luck
Reply:Hey,
What were the rest of her blood test results?
If she is anemic - something is wrong; rest of test should show bigger picture.
She has 2 of the "base symptoms" for a could of different deseases and cancers (such as Myeloma) but it could also be nothing - the pain killers (with long term use) could surpress the HGB and RBC.
Just like looking at one part of the body, the blood test is made up of many sections.
Good luck
Jewells
35 months and still here
Reply:Unfortunately the answer is yes...It took 9 months for the docs to diagnose my bone cancer and just told me to take Advil. Not until my blood work went to terrible did they decide something was wrong. I was fortunate I lived to tell the tale. I wish you and your family well.
flower
She's had bone pain in her arm for over one year now. One doctor diagnosed it as an arthritic joint in late 2005. Another put her on anti-inflammatories and physical therapy for bursitis/frozen shoulder in October of 2006. The drugs alleviated the bone pain a little bit but the shoulder joint and back and spine remained very achey. She looked uncomfortable and pale all of the time and I kept telling her that maybe she should see another doctor.
She finally went to a different doctor last week when she noticed some swollen lymph nodes in her neck. Her blood tests revealed that she's very anemic.
Do anti-inflammatories delay a correct diagnisis of cancer by masking/reducing bone pain? She's been looking unwell for a long time and unfortunately, her doctors only viewed her as a body part (in this case a shoulder) instead of a whole person who looked quite obviously, unwell. I'm just terribly worried about her
Reply:Lots of things can delay a correct diagnosis of cancer. Anti-inflammatory drugs or pain pills can mask pain but you would still have fever, weight loss or fatigue that would not be easily masked by anti-inflammatory medication.
Yes, the Dr should have looked at her as a whole person. Does she have an internist she sees at least once or twice a year that would have done blood work and noticed her declining health? If she is over thirty or so then she needs to see a Dr yearly at a minimum even if she isn't ill. When someone who doesn't see a Dr regularly comes in with a complaint about shoulder pain then the Dr treats the shoulder pain and cancer would not be their first thought.
From the symptoms you mentioned cancer is still just one possibility of a number of possible health problems so don't start assuming that this means she has cancer. There are a number of non cancer possibilities that need to be eliminated from consideration before she will have a diagnosis.
If your sister does turn out to have cancer my suggestion is to help your sister deal with her illness, be there for her, and help her remain positive each and every day. Don't waste time with the "what ifs" because it doesn't help you or her. good luck
Reply:Hey,
What were the rest of her blood test results?
If she is anemic - something is wrong; rest of test should show bigger picture.
She has 2 of the "base symptoms" for a could of different deseases and cancers (such as Myeloma) but it could also be nothing - the pain killers (with long term use) could surpress the HGB and RBC.
Just like looking at one part of the body, the blood test is made up of many sections.
Good luck
Jewells
35 months and still here
Reply:Unfortunately the answer is yes...It took 9 months for the docs to diagnose my bone cancer and just told me to take Advil. Not until my blood work went to terrible did they decide something was wrong. I was fortunate I lived to tell the tale. I wish you and your family well.
flower
Are there any dangers with certain anti perspirants?
91>Ive been told that breast cancer has been linked to anti perspirants. Im interested in trying a new one, Driclor but it sounds particularly strong, should i stay away?
Reply:I had read an article in Prevention magazine a while back that stated they couldn't find anything conclusive on this. The only time I've had issues with antiperspirants is when I went for my first mammogram; I hadn't been told that residue would show up on the x-ray and sure enough it did! Scared the hell out of me.
Reply:Yes.
Antiperspirant's all contain toxic substances. Aluminum Chlorhydrate is the most widely used. This is a heavy metal and is absorbed by the body where it ends up in ductless glands like the thyroid gland where it causes it to slow down.
It's amazing what we will do to not smell. I have found the perfect deodorant. It works so well, I have to remind myself to take a shower because it lasts for 2 - 3 days. It has no toxic chemicals and is very effective. One container lasts for about 3 - 4 months. You can purchase it from a web site: www.healthline.cc
You only have to use a very small amount under each arm. I looked for several months before I found this and it really works. I would never, ever go back to that store bought garbage.
good luck
Reply:I had read an article in Prevention magazine a while back that stated they couldn't find anything conclusive on this. The only time I've had issues with antiperspirants is when I went for my first mammogram; I hadn't been told that residue would show up on the x-ray and sure enough it did! Scared the hell out of me.
Reply:Yes.
Antiperspirant's all contain toxic substances. Aluminum Chlorhydrate is the most widely used. This is a heavy metal and is absorbed by the body where it ends up in ductless glands like the thyroid gland where it causes it to slow down.
It's amazing what we will do to not smell. I have found the perfect deodorant. It works so well, I have to remind myself to take a shower because it lasts for 2 - 3 days. It has no toxic chemicals and is very effective. One container lasts for about 3 - 4 months. You can purchase it from a web site: www.healthline.cc
You only have to use a very small amount under each arm. I looked for several months before I found this and it really works. I would never, ever go back to that store bought garbage.
good luck
Cancer fighting foods?
90>Can you tell me specifically what foods fight or prevent cancer and are there any anti aging foods? And how often do I eat them? Thanks
Reply:The number one risk factor for developing cancer is the accumulation of free radicals over time. On the other hand, eating high antioxidant foods may prevent cancer and slow premature aging. Over three decades worth of epidemiological studies show that a diet high in fruits dramatically reduces reactive oxygen species and, therefore, the risk of every major type of cancer.
In addition to smart dietary choices, maintaining a strong immune system and healthy liver also play vital roles in slowing the onset of cancer.
As one of the most powerful whole-food liver protectants studied, the Ningxia wolfberry has the potential to supercharge liver detoxification and raise almost all measures of a healthy immune system.
Studies show that blueberries and raspberries offer the best protection against free radicals. They can improve mental functioning and actually reverse aging.
ACS recommends that you eat 5 or more servings of a variety of vegetables and fruits each day. Try adding high antioxidant berries to your diet.
Best wishes.
.
Reply:i remember being told to eat all the variety of fruits and veggies also to avoid burning foods and limit red meat and processed junk
Reply:rasin carrott
Reply:veggies, fruits, and cereal
Reply:any vegetable or fruit that is red or purple is a cancer fighter because it contain antioxodants that fight cance. Also I knew some one who had a brain tumor and he took shark liver oil and 2 months later the CAT scan showed that the tumor disappeared.
Reply:sulfur foods like garlic and onions. the national cancer institute has a page on it. try a search to find that page. sorry i dont know how to paste the address.
Reply:The number one risk factor for developing cancer is the accumulation of free radicals over time. On the other hand, eating high antioxidant foods may prevent cancer and slow premature aging. Over three decades worth of epidemiological studies show that a diet high in fruits dramatically reduces reactive oxygen species and, therefore, the risk of every major type of cancer.
In addition to smart dietary choices, maintaining a strong immune system and healthy liver also play vital roles in slowing the onset of cancer.
As one of the most powerful whole-food liver protectants studied, the Ningxia wolfberry has the potential to supercharge liver detoxification and raise almost all measures of a healthy immune system.
Studies show that blueberries and raspberries offer the best protection against free radicals. They can improve mental functioning and actually reverse aging.
ACS recommends that you eat 5 or more servings of a variety of vegetables and fruits each day. Try adding high antioxidant berries to your diet.
Best wishes.
.
Reply:i remember being told to eat all the variety of fruits and veggies also to avoid burning foods and limit red meat and processed junk
Reply:rasin carrott
Reply:veggies, fruits, and cereal
Reply:any vegetable or fruit that is red or purple is a cancer fighter because it contain antioxodants that fight cance. Also I knew some one who had a brain tumor and he took shark liver oil and 2 months later the CAT scan showed that the tumor disappeared.
Reply:sulfur foods like garlic and onions. the national cancer institute has a page on it. try a search to find that page. sorry i dont know how to paste the address.
How to minimize cancer affliction?
89>I have answers no one has showed yet. Cancer caused by the environment. no one escapes from it. Oxidants, toxin are causes of cancer. We need negatively charged minerals to combat cancer. They are the best anti-oxidant. where do we find it. visit www.samaritanhealthproducts.com. When a cell becomes unbalanced whether it is plant or animal/human cell, oxidants will attack the cell because it is weak. once the cell is more positive it will also look for another unbalance cell making a change reaction. the more weak cells we have the more we easilyt get sick. We need to polarize our cells, meaning increase the electrical cahrge of the cell. This is a simple science that we overlook. We are taught to look to food of plants and fruits for anti oxidant, not knowing that these also have toxin with them. so it only works if there is more antioxdant that toxin in these food group. sometimes very little difference. My advice is to look for minerals that are negatively charged. We have it.
Reply:well you seem set on your approach but here is another approach that actually has a guarantee and over 30 yrs of clinical experience behind it Basically what cancer is is the body response to an overwhelmed immune system it breaks down do to monochromal expansion and not enough Killer T cells that attack foreign invaders one such example is the lymphocytes and phagocytes that attack things foreign to the body then the body steps up production of antibodies that attack diseased organisms and cells now the t cells should replicate 50x however when you immune system is compromised they only replicate like 20x so there is not enough protection and soon the cancerous cells inject a mutated form of messenger Rna into healthy cells and they start making more cancer cells so to fight back you have to give the body what it needs and the thing it needs most is to raise the bodys master antioxidant level and the BEST WAY to do this is to give the body what it needs to make more of the key ingredient in the immune system called Glutathione peroxidase (not found in any health food store) but you can give it the bonded cystine molecules it needs to make it ie Glutamic Acid, Glycine, and Cystine that must be in a Bonded Sulfur molecule or it is destroyed on digestion and the only source of such is a product called immunocal it has a 99.5% success rate in dealing with Cancer and other auto immune diseases by raising the Bodys intracellular Glutathione levels this process has 10 GLOBAL METHOD OF USE PATTENTS and backed by the top people in the field worldwide hope this helps gorbalizer
Reply:What a load of rubbish.
Reply:well you seem set on your approach but here is another approach that actually has a guarantee and over 30 yrs of clinical experience behind it Basically what cancer is is the body response to an overwhelmed immune system it breaks down do to monochromal expansion and not enough Killer T cells that attack foreign invaders one such example is the lymphocytes and phagocytes that attack things foreign to the body then the body steps up production of antibodies that attack diseased organisms and cells now the t cells should replicate 50x however when you immune system is compromised they only replicate like 20x so there is not enough protection and soon the cancerous cells inject a mutated form of messenger Rna into healthy cells and they start making more cancer cells so to fight back you have to give the body what it needs and the thing it needs most is to raise the bodys master antioxidant level and the BEST WAY to do this is to give the body what it needs to make more of the key ingredient in the immune system called Glutathione peroxidase (not found in any health food store) but you can give it the bonded cystine molecules it needs to make it ie Glutamic Acid, Glycine, and Cystine that must be in a Bonded Sulfur molecule or it is destroyed on digestion and the only source of such is a product called immunocal it has a 99.5% success rate in dealing with Cancer and other auto immune diseases by raising the Bodys intracellular Glutathione levels this process has 10 GLOBAL METHOD OF USE PATTENTS and backed by the top people in the field worldwide hope this helps gorbalizer
Reply:What a load of rubbish.
I don’t want to use anti-perspirant deodorant anymore!?
88>I want to switch to something without “ALUMINUM” in it. I heard that anti-perspirant deodorant give breast cancer. Do anyone in here know what brand of deodorant is good because I want something that will makes me smell good and healthy. Thank you for your help.
Aurevoir.
Reply:It does NOT cause breast cancer!!!
Reply:secret
Reply:Check in the organic food stores. Since regular grocery stores carry regular health and hygiene items, maybe organic grocery stores carry organic health and hygiene items. Aluminum has also been linked to Alzhiemer's.
Reply:there is a brand of addidas deodarant that says aluminium free u could try that
Reply:you can get botox injections and then you wont need to use deoderant. Thats what my mom does
Reply:I tried to get away from anti-perspirants, but can't stand the feeling of wet armpits. Deodorants will keep you from smelling, but won't keep you dry. I guess frequent showers would help, too, but most people have to work, and can't shower 5x a day!!! It's the aluminum that keeps you dry. I have heard some folks like those solid crystals that you wet and rub on your skin. I tried it, and didn't like it. I fear getting Alzheimers, (they feel there is a link there)but at least I won't smell for the next few decades. I read that the anti perspirant and breast cancer link was an internet hoax. Check out snopes.com to see if they feel it's a hoax.
Reply:get some tom's its all natural deoderant
Reply:oraganic
flower arrangements
Aurevoir.
Reply:It does NOT cause breast cancer!!!
Reply:secret
Reply:Check in the organic food stores. Since regular grocery stores carry regular health and hygiene items, maybe organic grocery stores carry organic health and hygiene items. Aluminum has also been linked to Alzhiemer's.
Reply:there is a brand of addidas deodarant that says aluminium free u could try that
Reply:you can get botox injections and then you wont need to use deoderant. Thats what my mom does
Reply:I tried to get away from anti-perspirants, but can't stand the feeling of wet armpits. Deodorants will keep you from smelling, but won't keep you dry. I guess frequent showers would help, too, but most people have to work, and can't shower 5x a day!!! It's the aluminum that keeps you dry. I have heard some folks like those solid crystals that you wet and rub on your skin. I tried it, and didn't like it. I fear getting Alzheimers, (they feel there is a link there)but at least I won't smell for the next few decades. I read that the anti perspirant and breast cancer link was an internet hoax. Check out snopes.com to see if they feel it's a hoax.
Reply:get some tom's its all natural deoderant
Reply:oraganic
flower arrangements
Deoderant and Cancer?
87>I was told that anti-persperant deoderants can cause cancer. is this true?
Reply:Actually it's still in debate.
Feb. 28, 2006 -- Does regular use of antiperspirants increase a woman's risk for developing breast cancer? A researcher in the U.K. says the answer could very well be yes, but experts tell WebMD that there is still little evidence to back up the claim.
The antiperspirant-breast cancer claim has achieved something akin to urban legend status on the Internet and in the popular press, despite that fact that few clinical studies in humans have addressed the issue.
One of the strongest, published in 2002, found no link between antiperspirant or deodorant use and breast cancer risk. Researchers compared usage patterns among roughly 800 breast cancer patients and a similar number of women without the disease.
But cancer researcher Philippa Darbre, PhD, of the University of Reading in England, sees it differently. She says the evidence is mounting that the aluminum-based active ingredient in antiperspirants can mimic estrogen in the body.
"Lifetime exposure to estrogen is the risk factor which is tied most strongly to breast cancer," Darbre tells WebMD. "If the aluminum salts in antiperspirants enter the body and mimic estrogen it stands to reason that constant exposure over many years may pose a risk."
Reply:I heard the same thing several years ago, but I haven't heard anything since so I'm assuming it was a fluke. They haven't done any recalls or pulled any off the shelves so I would say it's nothing to worry about.
Reply:i know that when you are tested for cancer if you are being tested around where you have deoderant on it may send up a red flag to docters but i havent heard much about it causing cancer
Reply:There was an e-mail circulating linking using deodorant to breast cancer. Don't believe everything you read, this is a myth. There is no scientific evidence to support this claim.
Read this article called "Antiperspirants and Breast Cancer Risk" from the American Cancer Society.
http://www.cancer.org/docroot/MED/conten...
Reply:Anti-perspirants have aluminum chlorohydrate in them which helps "keep you dry". Unfortunately, daily use of an anti-perspirant on the tender skin of the underarm can lead to skin rashes, peeling skin (painful in that area, too!) and the aluminum can be absorbed into the blood stream contributing to a weakening of the bones. There was also a link to Alzheimer's but I don't know if that has been proved or is still in the rumor stage.
DEODORANTS do NOT contain this nasty form of aluminum and although they do not claim to keep you "dry", they will help to reduce odor.
Read labels carefully--it's good that you are paying attention and asking questions
Hope this helps.
Reply:Try using a deodorant made by natural substances if you are concerned. Try out Tom's of Maine.
Reply:Research has said this, but the main thing that you should do is to shave your underarms at night because when you shave you are breaking the skin open and then putting on your deodorant. Not good. There are large amounts of aluminum in these products. Adidas makes a deodorant that does not have the aluminum in it. Later through the day you do get some BO but it is really not that bad, just carry it w/ you and reapply. Good luck. Just remember do NOT shave then apply deodorant w/ these chemicals in them. If you look at you deodorant it says DO NOT APPLY ON BROKEN SKIN!
Reply:The brands of antiperspirants have aluminum in them that has been linked to cancer and brain neurological diseases . I use Naturals brand with baking soda made by the Melaluca company
Reply:There has been a lot of research done in the past few years about weather deordant use leads to cancer. Research so far has come back undecided. Some medical field professionals will insist that there is no link to cancer from the use of deoradant while others will beg to differ. But also ask yourself this question. How many of the daily things do we use or wear cause cancer? Life is full of risk with whatever we do. Below is some research information regarding deordant and cancer. I hope you find this information useful. Best of luck to you and take care.
Breast cancer- deodorant link 'needs more evidence'
1/ 3/2006
MORE research is needed to examine whether there is a link between using antiperspirants and the risk of breast cancer, an expert said today.
Chemicals that mimic the body's natural hormone oestrogen are known to affect a woman's risk of breast cancer, according to the review in the Journal of Applied Toxicology.
Dr Philippa Darbre said evidence was mounting that an aluminium-based compound, which often makes up a quarter of the volume of some antiperspirant agents, can break through the skin and once in the body could mimic oestrogen.
The researcher, from the University of Reading, called for further study to evaluate whether this process could increase the risk of breast cancer.
The review said that in recent years scientists had found that many compounds in the environment interact with oestrogen.
These compounds are normally complex molecules and are found in many plants and are used in materials like detergents, pesticides and plastics.
But now scientists believe that a variety of simple metal ions, including aluminium and cadmium, can also bind with the body's oestrogen receptors and influence their action.
Dr Darbre, from the School of Biological Sciences, said: "Since oestrogen is known to be involved in the development and progression of human breast cancer, any components of the environment that have oestrogenic activity and which can enter the human breast could theoretically influence a woman's risk of breast cancer."
She said that aluminium salts in antiperspirants were a major source of human exposure to aluminium.
These products are often sprayed into the armpits - concentrating exposure near to the breast.
The review also noted that such products were also often applied immediately after shaving, when the skin was more likely to be damaged and less able to keep the aluminium out.
"It is reasonable to question whether this aluminium could then influence breast cancer," Dr Darbre said.
The researcher said there were also concerns about potential links between smoking and breast cancer.
The review said that tobacco introduced cadmium into the body, with research showing that it can collect in breast tissue.
Dr Darbre said that were indications that the accumulation of cadmium may also be linked to an increased risk of breast cancer.
She added: "Each of these agents on their own may not have a powerful effect, but we need to see what happens when a number of them act together - it could be that this would have a significant effect on diseases like breast cancer."
Liz Carroll, head of clinical services at Breast Cancer Care, said: "As the extent to which lifestyle and environmental factors increase the risk of developing breast cancer is still uncertain, Breast Cancer Care always welcomes new research into this area, where much still needs to be learnt.
"Research studies to date have found no proven link between the use of deodorants and the risk of developing breast cancer.
"More extensive research in this area is needed to fully determine whether there is a link, and to enable people to make a more informed decision about deodorant use.
"We hear from people with breast cancer or breast health concerns daily through our helpline and website, and know how research into risk factors for breast cancer can cause anxiety.
"It is important however for all people to be aware that age remains the single biggest risk factor."
Dr Sarah Rawlings, head of policy and information at Breakthrough Breast Cancer, said: "There is no reliable scientific evidence to suggest a link between deodorant or antiperspirant use - both on their own and in combination with shaving - and breast cancer.
"A large number of scientific studies have investigated breast cancer risk factors. However, there is no reliable evidence to suggest deodorant or antiperspirant use are two of them.
"This review does not provide any further proof.
"Breast cancer is a complex disease and its causes are unknown for the majority of the 41,000 women diagnosed each year in the UK.
"That's why Breakthrough Breast Cancer supports the Breakthrough Generations Study - the largest study of its kind in the UK to investigate the causes of breast cancer and to gain information on causes that might be preventable."
Reply:Actually it's still in debate.
Feb. 28, 2006 -- Does regular use of antiperspirants increase a woman's risk for developing breast cancer? A researcher in the U.K. says the answer could very well be yes, but experts tell WebMD that there is still little evidence to back up the claim.
The antiperspirant-breast cancer claim has achieved something akin to urban legend status on the Internet and in the popular press, despite that fact that few clinical studies in humans have addressed the issue.
One of the strongest, published in 2002, found no link between antiperspirant or deodorant use and breast cancer risk. Researchers compared usage patterns among roughly 800 breast cancer patients and a similar number of women without the disease.
But cancer researcher Philippa Darbre, PhD, of the University of Reading in England, sees it differently. She says the evidence is mounting that the aluminum-based active ingredient in antiperspirants can mimic estrogen in the body.
"Lifetime exposure to estrogen is the risk factor which is tied most strongly to breast cancer," Darbre tells WebMD. "If the aluminum salts in antiperspirants enter the body and mimic estrogen it stands to reason that constant exposure over many years may pose a risk."
Reply:I heard the same thing several years ago, but I haven't heard anything since so I'm assuming it was a fluke. They haven't done any recalls or pulled any off the shelves so I would say it's nothing to worry about.
Reply:i know that when you are tested for cancer if you are being tested around where you have deoderant on it may send up a red flag to docters but i havent heard much about it causing cancer
Reply:There was an e-mail circulating linking using deodorant to breast cancer. Don't believe everything you read, this is a myth. There is no scientific evidence to support this claim.
Read this article called "Antiperspirants and Breast Cancer Risk" from the American Cancer Society.
http://www.cancer.org/docroot/MED/conten...
Reply:Anti-perspirants have aluminum chlorohydrate in them which helps "keep you dry". Unfortunately, daily use of an anti-perspirant on the tender skin of the underarm can lead to skin rashes, peeling skin (painful in that area, too!) and the aluminum can be absorbed into the blood stream contributing to a weakening of the bones. There was also a link to Alzheimer's but I don't know if that has been proved or is still in the rumor stage.
DEODORANTS do NOT contain this nasty form of aluminum and although they do not claim to keep you "dry", they will help to reduce odor.
Read labels carefully--it's good that you are paying attention and asking questions
Hope this helps.
Reply:Try using a deodorant made by natural substances if you are concerned. Try out Tom's of Maine.
Reply:Research has said this, but the main thing that you should do is to shave your underarms at night because when you shave you are breaking the skin open and then putting on your deodorant. Not good. There are large amounts of aluminum in these products. Adidas makes a deodorant that does not have the aluminum in it. Later through the day you do get some BO but it is really not that bad, just carry it w/ you and reapply. Good luck. Just remember do NOT shave then apply deodorant w/ these chemicals in them. If you look at you deodorant it says DO NOT APPLY ON BROKEN SKIN!
Reply:The brands of antiperspirants have aluminum in them that has been linked to cancer and brain neurological diseases . I use Naturals brand with baking soda made by the Melaluca company
Reply:There has been a lot of research done in the past few years about weather deordant use leads to cancer. Research so far has come back undecided. Some medical field professionals will insist that there is no link to cancer from the use of deoradant while others will beg to differ. But also ask yourself this question. How many of the daily things do we use or wear cause cancer? Life is full of risk with whatever we do. Below is some research information regarding deordant and cancer. I hope you find this information useful. Best of luck to you and take care.
Breast cancer- deodorant link 'needs more evidence'
1/ 3/2006
MORE research is needed to examine whether there is a link between using antiperspirants and the risk of breast cancer, an expert said today.
Chemicals that mimic the body's natural hormone oestrogen are known to affect a woman's risk of breast cancer, according to the review in the Journal of Applied Toxicology.
Dr Philippa Darbre said evidence was mounting that an aluminium-based compound, which often makes up a quarter of the volume of some antiperspirant agents, can break through the skin and once in the body could mimic oestrogen.
The researcher, from the University of Reading, called for further study to evaluate whether this process could increase the risk of breast cancer.
The review said that in recent years scientists had found that many compounds in the environment interact with oestrogen.
These compounds are normally complex molecules and are found in many plants and are used in materials like detergents, pesticides and plastics.
But now scientists believe that a variety of simple metal ions, including aluminium and cadmium, can also bind with the body's oestrogen receptors and influence their action.
Dr Darbre, from the School of Biological Sciences, said: "Since oestrogen is known to be involved in the development and progression of human breast cancer, any components of the environment that have oestrogenic activity and which can enter the human breast could theoretically influence a woman's risk of breast cancer."
She said that aluminium salts in antiperspirants were a major source of human exposure to aluminium.
These products are often sprayed into the armpits - concentrating exposure near to the breast.
The review also noted that such products were also often applied immediately after shaving, when the skin was more likely to be damaged and less able to keep the aluminium out.
"It is reasonable to question whether this aluminium could then influence breast cancer," Dr Darbre said.
The researcher said there were also concerns about potential links between smoking and breast cancer.
The review said that tobacco introduced cadmium into the body, with research showing that it can collect in breast tissue.
Dr Darbre said that were indications that the accumulation of cadmium may also be linked to an increased risk of breast cancer.
She added: "Each of these agents on their own may not have a powerful effect, but we need to see what happens when a number of them act together - it could be that this would have a significant effect on diseases like breast cancer."
Liz Carroll, head of clinical services at Breast Cancer Care, said: "As the extent to which lifestyle and environmental factors increase the risk of developing breast cancer is still uncertain, Breast Cancer Care always welcomes new research into this area, where much still needs to be learnt.
"Research studies to date have found no proven link between the use of deodorants and the risk of developing breast cancer.
"More extensive research in this area is needed to fully determine whether there is a link, and to enable people to make a more informed decision about deodorant use.
"We hear from people with breast cancer or breast health concerns daily through our helpline and website, and know how research into risk factors for breast cancer can cause anxiety.
"It is important however for all people to be aware that age remains the single biggest risk factor."
Dr Sarah Rawlings, head of policy and information at Breakthrough Breast Cancer, said: "There is no reliable scientific evidence to suggest a link between deodorant or antiperspirant use - both on their own and in combination with shaving - and breast cancer.
"A large number of scientific studies have investigated breast cancer risk factors. However, there is no reliable evidence to suggest deodorant or antiperspirant use are two of them.
"This review does not provide any further proof.
"Breast cancer is a complex disease and its causes are unknown for the majority of the 41,000 women diagnosed each year in the UK.
"That's why Breakthrough Breast Cancer supports the Breakthrough Generations Study - the largest study of its kind in the UK to investigate the causes of breast cancer and to gain information on causes that might be preventable."
Anti-perspirant- or regular deoderant while pregnant?
86>ive heard that d/o containing Anti-perspiant can cause breast cancer... does any one know the truth about this and is it better to use a d/o without antiperspirant during pregnancy?
Reply:if it was bad then it would be known, it's most likely a myth. i was preg and the only things i remember the dr told me of 1st off was taking meds of course, cats and fingernail polish/remover. so yeah not true. or we all would have Breast Cancer.
Reply:To tell you the truth, I think that's all a big myth. I wouldn't change my anti-perspirant if I were pregnant. If I switched to just deodorant, I would have big embarrassing sweat marks all the time. ewww....
Reply:i dont really think it is true. think of the MILLIONS of people, not just women that would have breast cancer. i used the same stuff all while i was preggo
Reply:Does not matter. I am pregnant and with summer coming up can't even believe that anyone would be afraid to use it. No medical studies have proved it - old wives tale. If you are super-concerned asked your ob, but I'm pretty positive you will be told that it i safe to use.
Reply:if it was bad then it would be known, it's most likely a myth. i was preg and the only things i remember the dr told me of 1st off was taking meds of course, cats and fingernail polish/remover. so yeah not true. or we all would have Breast Cancer.
Reply:To tell you the truth, I think that's all a big myth. I wouldn't change my anti-perspirant if I were pregnant. If I switched to just deodorant, I would have big embarrassing sweat marks all the time. ewww....
Reply:i dont really think it is true. think of the MILLIONS of people, not just women that would have breast cancer. i used the same stuff all while i was preggo
Reply:Does not matter. I am pregnant and with summer coming up can't even believe that anyone would be afraid to use it. No medical studies have proved it - old wives tale. If you are super-concerned asked your ob, but I'm pretty positive you will be told that it i safe to use.
Food feeling stuck in chest-possible thryoid cancer - something else?
85>Hello, I don't even know where to begin. I have a thyroid nodule that has been biopsed and I am waiting for the results. I can feel the nodule when I swallow. I am so nervous that I have thryoid cancer that I took anti anxiety pills, but now stopped. Took some trazadone to sleep but now stopped. I was getting sharp chest pains and felt food sticking in my throat halfway down in esophoges. So, I started prilosec thinking I might have GERD. Could stress cause GERD? Well, the chest pains are gone, but the food stuck in my throat feeling is still there. So, then I thought that was from the possible thyroid cancer. So I asked my endicrinologist and he said they are not related. So, I am at a loss what this is from. I am so freaked out I have cancer and it has spread down my esophages from my thyroid. Anyone know what this is from? Also, other symptom since this all started is morning congestion every morning. Never had that before either. (2 months now) Please help me?
Reply:Hi hun,
I'm sure what your going through right now is very worrying, but what you need to do right now is calm down. You would be surprised what stress and anxiety can do to you. If you convince yourself you have an illness you can experience a whole new range of symptoms. Might sound a bit strange but i speak from experience! These chest pains could be panic attacks and many people experience a feeling of a lump in the throat which seems to go down and come back up after swallowing. Hope this helps and good luck i'm sure you'll be fine :)
Reply:Calm down. The more you freak out and worry, the worse you are going to think your symptoms are. Nodules on the thyroid are very common and are usually NOT cancerous. Yes, stress can cause terrible reflux and indigestion. If you keep thinking that there is something terribly wrong with you, you will imagine all kinds of things.
Reply:Call your Dr., you need reassurance. First of all, 90% of all thyroid cancers have a survival rate on the 95% + range. Your stress is causing you to have pyschosomatic symptoms.
Reply:You can have benign growths My sister had a golf ball sized lump on her throat and they thought for sure it was lymphoma. I prayed to God for her to be alright and it gradually went away in a couple of weeks. Hiatal hernias can press against the heart if they are big enough. Do you smoke? If so please consider giving that up to prevent mouth/throat/lung cancer.
Have you tried the St. Jude novena? You pray it for nine days. Danny Thomas prayed it when he was a struggling comedian and he later succeeded at his profession and then went on to build St. Jude's Reseach hospital for children with cancer.St. Jude is the patron saint of hopeless causes....see link below.
Reply:If food is getting stuck in your esophagus, you either have a web, adhesions, or a motility disorder.
The morning congestion can be a result of nocturnal reflux, especially if it is foul-tasting. See a gastroenterologist.
You can sleep propped up at a 30 degree angle to prevent the reflux from reaching your throat. Take a good antacid before bed, avoid fatty foods and caffiene, as well as alcoholic beverages.
Reply:I can really sympathize with you, but the best thing you could do right now is relax, even if it's with the help of medication. The more anxious you are, the worse your stress is and the worse your reflux will be. Thyroid nodules are very rarely cancerous. Most are due to benign conditions, so I wouldn't worry about your thyroid. Reflux can also cause congestion. It sounds like a lot of your symptoms are stress-related, so talk to your doctor about relieving your stress.
Reply:Hi hun,
I'm sure what your going through right now is very worrying, but what you need to do right now is calm down. You would be surprised what stress and anxiety can do to you. If you convince yourself you have an illness you can experience a whole new range of symptoms. Might sound a bit strange but i speak from experience! These chest pains could be panic attacks and many people experience a feeling of a lump in the throat which seems to go down and come back up after swallowing. Hope this helps and good luck i'm sure you'll be fine :)
Reply:Calm down. The more you freak out and worry, the worse you are going to think your symptoms are. Nodules on the thyroid are very common and are usually NOT cancerous. Yes, stress can cause terrible reflux and indigestion. If you keep thinking that there is something terribly wrong with you, you will imagine all kinds of things.
Reply:Call your Dr., you need reassurance. First of all, 90% of all thyroid cancers have a survival rate on the 95% + range. Your stress is causing you to have pyschosomatic symptoms.
Reply:You can have benign growths My sister had a golf ball sized lump on her throat and they thought for sure it was lymphoma. I prayed to God for her to be alright and it gradually went away in a couple of weeks. Hiatal hernias can press against the heart if they are big enough. Do you smoke? If so please consider giving that up to prevent mouth/throat/lung cancer.
Have you tried the St. Jude novena? You pray it for nine days. Danny Thomas prayed it when he was a struggling comedian and he later succeeded at his profession and then went on to build St. Jude's Reseach hospital for children with cancer.St. Jude is the patron saint of hopeless causes....see link below.
Reply:If food is getting stuck in your esophagus, you either have a web, adhesions, or a motility disorder.
The morning congestion can be a result of nocturnal reflux, especially if it is foul-tasting. See a gastroenterologist.
You can sleep propped up at a 30 degree angle to prevent the reflux from reaching your throat. Take a good antacid before bed, avoid fatty foods and caffiene, as well as alcoholic beverages.
Reply:I can really sympathize with you, but the best thing you could do right now is relax, even if it's with the help of medication. The more anxious you are, the worse your stress is and the worse your reflux will be. Thyroid nodules are very rarely cancerous. Most are due to benign conditions, so I wouldn't worry about your thyroid. Reflux can also cause congestion. It sounds like a lot of your symptoms are stress-related, so talk to your doctor about relieving your stress.
ALUMINUM CHLOROHYDRATE and CANCER?
84>Can Aluminum Chlorohydrate one of the ingredients used in making Anti-persirant deodorant cause cancer?
Reply:don't know that one, but i heard it contributes to getting Alzheimers.
Reply:NO. Urban Legend.
Reply:don't know that one, but i heard it contributes to getting Alzheimers.
Reply:NO. Urban Legend.
Anti perspirants or deodorant?
83>okay....my first question is which one lass longer..
and my second is...is is true the anti-pespirants cause cancer or something like that????
Reply:They don't cause cancer.
That was an old myth!!
deoderant controls oder and only will work if you first use it out of the shower. YOU CANNOT put it on if you aren't clean.
It just won't work!
Anti-perspirants, are just that, they help lower your perspiration.
meaning they help to control your sweat! The less you sweat, the less stinky oils are released. It's the sweaty bacteria, that we sweat when we are nervous, anxious, or playing a sport that is smelly.
So, if you don't sweat a lot, use deoderant, and if you are a heavy perspirer, meaning if you sweat a lot and want to control the wet underarm problem, then use an anti-perspirant.
Tom's is the most natural.
I like Dry Idea by Gillette. It's a clear gel. Unscented.
Sauve makes some nice scents too. go unscented, or fresh.
www.gillette.com
start with an unscented, and you will feel better.
Use it after you dry off from your shower or bath.
Reply:not true
Reply:i can't answer either of those questions but i will tell you the aluminum in anti-perpirants is linked to alheizmers disease.
Reply:one thing I do know is that both clog up your pores. and sweating is our natural way we cool ourselves.
Reply:cough cough... retard
ok, anti-perspirants do not cause cancer, and they keep you from perspirating, deodarant is just a spray that makes you smell
Reply:Antiperpirants clog your pores. The powder gets absorbed into pores and swell up with sweat preventing sweat from coming out.
I try to avoid that but it is hard to find deodorants that aren't antiperpirants.Antiperpirants just have antibacterial stuff that stops smelly bacteria from growing.
Speed stick is the only one I can find.
Reply:you want to find something that is both an anti perspirant and a deodorant (it just doesn't work well otherwise).
And no, it's not true that they cause cancer.
Reply:Anti perspirants clogs you re pores stay away from that, deodorant will do.
Reply:Both last the same amount of time, it's the different brands that have different lasting effects. Anti-persperants are not known to cause cancer, but they are unhealthy for you. All the sweat is trapped inside your pores, creating rashes and skin disorders. It's always best to use a deodorant to cover up the smell.
Reply:It's a theory they are throwing around. There has been a link between women and breast cancer. It's because it contains Aluminum chlorohydrate, and or aluminum zirconium. There have been many other studies done linking it to things like Alzheimer's, Reproductive problems, and cancer. I wouldn't worry too much though.
Reply:Well,
It all depends on what you are looking for. Deoderant will last longer since it is more soild and can retain its hold better. Anti-Prespirants will go on quicker but most have a better scent but the usually dont last as long.
So it comes down to do you want to not smell as much for a longer time or Do you want to smell really nice for a shorter time.
Reply:The difference between them is that a deodourant will get rid of the odor causing bacteria whereas anti-perspirant stops you from sweating by using chemicals. For most people, a simple deodorant will do the job. Only people who sweat excessively (like a lot more) or who have extreme odour problems should use anti-persperant.
For if anti-persperant causes cancer, I am not aware of a specific study that proves this but I am aware that the chemicals used can harm you skin and even be absorbed by your body. Like anything, the less chemicals your body absorbs, the better it is. Deodorants have weaker chemicals and are therefore the best choice.
Reply:Anti perspirant blocks the pores where the sweat comes from.with deoderant,you still sweat,but it does not smell.,neither one causes cancer,but anti perspirspirants sometimes cause skin problems.
Reply:Because I prefer using the one that dries when I apply it rather than have to "wave my arms like the Funky Chicken", I use a deodorant. - (The Anti-persp's usually come in a solid stick.)
GRANTED, the dry stick (anti-persp) does usually last longer, it is such a hassle to apply.
And the drying alchohol in either does irritate my underarm skin.
Reply:Some doctors say underarm deoderant is a link to breast cancer .Try not to use to much and dont use it if you dont have to.
and my second is...is is true the anti-pespirants cause cancer or something like that????
Reply:They don't cause cancer.
That was an old myth!!
deoderant controls oder and only will work if you first use it out of the shower. YOU CANNOT put it on if you aren't clean.
It just won't work!
Anti-perspirants, are just that, they help lower your perspiration.
meaning they help to control your sweat! The less you sweat, the less stinky oils are released. It's the sweaty bacteria, that we sweat when we are nervous, anxious, or playing a sport that is smelly.
So, if you don't sweat a lot, use deoderant, and if you are a heavy perspirer, meaning if you sweat a lot and want to control the wet underarm problem, then use an anti-perspirant.
Tom's is the most natural.
I like Dry Idea by Gillette. It's a clear gel. Unscented.
Sauve makes some nice scents too. go unscented, or fresh.
www.gillette.com
start with an unscented, and you will feel better.
Use it after you dry off from your shower or bath.
Reply:not true
Reply:i can't answer either of those questions but i will tell you the aluminum in anti-perpirants is linked to alheizmers disease.
Reply:one thing I do know is that both clog up your pores. and sweating is our natural way we cool ourselves.
Reply:cough cough... retard
ok, anti-perspirants do not cause cancer, and they keep you from perspirating, deodarant is just a spray that makes you smell
Reply:Antiperpirants clog your pores. The powder gets absorbed into pores and swell up with sweat preventing sweat from coming out.
I try to avoid that but it is hard to find deodorants that aren't antiperpirants.Antiperpirants just have antibacterial stuff that stops smelly bacteria from growing.
Speed stick is the only one I can find.
Reply:you want to find something that is both an anti perspirant and a deodorant (it just doesn't work well otherwise).
And no, it's not true that they cause cancer.
Reply:Anti perspirants clogs you re pores stay away from that, deodorant will do.
Reply:Both last the same amount of time, it's the different brands that have different lasting effects. Anti-persperants are not known to cause cancer, but they are unhealthy for you. All the sweat is trapped inside your pores, creating rashes and skin disorders. It's always best to use a deodorant to cover up the smell.
Reply:It's a theory they are throwing around. There has been a link between women and breast cancer. It's because it contains Aluminum chlorohydrate, and or aluminum zirconium. There have been many other studies done linking it to things like Alzheimer's, Reproductive problems, and cancer. I wouldn't worry too much though.
Reply:Well,
It all depends on what you are looking for. Deoderant will last longer since it is more soild and can retain its hold better. Anti-Prespirants will go on quicker but most have a better scent but the usually dont last as long.
So it comes down to do you want to not smell as much for a longer time or Do you want to smell really nice for a shorter time.
Reply:The difference between them is that a deodourant will get rid of the odor causing bacteria whereas anti-perspirant stops you from sweating by using chemicals. For most people, a simple deodorant will do the job. Only people who sweat excessively (like a lot more) or who have extreme odour problems should use anti-persperant.
For if anti-persperant causes cancer, I am not aware of a specific study that proves this but I am aware that the chemicals used can harm you skin and even be absorbed by your body. Like anything, the less chemicals your body absorbs, the better it is. Deodorants have weaker chemicals and are therefore the best choice.
Reply:Anti perspirant blocks the pores where the sweat comes from.with deoderant,you still sweat,but it does not smell.,neither one causes cancer,but anti perspirspirants sometimes cause skin problems.
Reply:Because I prefer using the one that dries when I apply it rather than have to "wave my arms like the Funky Chicken", I use a deodorant. - (The Anti-persp's usually come in a solid stick.)
GRANTED, the dry stick (anti-persp) does usually last longer, it is such a hassle to apply.
And the drying alchohol in either does irritate my underarm skin.
Reply:Some doctors say underarm deoderant is a link to breast cancer .Try not to use to much and dont use it if you dont have to.
Can men get breast cancer?
82>I was just wondering if men can get breast cancer. If they can't, then I'm gonna start using anti antiperspirant again. anti antiperspirant causes cancer right?
Reply:of course men can get breast cancer
here are the symptoms to look for
# hanges to the breast behind the nipple:
- Normally lumps that can be felt
- A firm mass directly underneath the nipple
# Nipples turning inwards
# Discharge from the nipple, which can be bloody
# Pain and itchy nipple
# Skin ulceration
# Lump under the arm
# Redness of the skin.
here are a few questions and answrs which are very interesting
Q: What is the ratio between men and women for survival from breast cancer?
It is said less in men due to poor prognosis.
Q: Why don't men know that they have breast cancer?
Because the majority of men don't know they can get it so ignore the changes or warning signs that would enable them to know. Also most females don't realise that men can get breast cancer.
Q: What percentage of men are diagnosed with breast cancer?
At time of writing (Oct 2005), 1 in 100 or 1%, compared with 1 in 14 women.
Q: Most breast cancer occurs in males aged between the ages of 60 and 70?
Yes. From the little information that does exist, it appears this is the case, but don't let that make you complacent, as Kym (whose story is here in our website) was 45 years old, Troy Smith a Cross Country Coach in Birmingham was 33 years old and Jason Foy from the UK was only 29 years old and sadly died at 33 years in 2004.
Click here to read Kym鈥檚 story.
with regards to anti antiperspirant Aluminum, a common ingredient added to antiperspirants to stop skin sweating, may be linked to breast cancer, a study by British scientists found.
Reply:yes men can although it is rarer in men but there is no evidence that antiperspirant causes cancer
Reply:Yes men can get breast cancer. There is no proof that anti-perspirants cause cancer. No one knows what causes cancer.
Reply:Yes John they can but under arm stuff dont cause it ...
Reply:yes men can defiantly have breast cancer, its just not known because they advertise women breast cancer and women are most likely to have it... There has been tons of warnings circulated through email and the internet that the use of deodorants and antiperspirants can cause breast cancer. The suggestion is that a chemical is absorbed through the skin through a shaving nick or cut, and causes breast cancer.
According to the National Cancer Institute, "researchers at the National Cancer Institute (NCI) are not aware of any conclusive evidence linking the use of underarm antiperspirants or deodorants and the subsequent development of breast cancer. The U.S. Food and Drug Administration, which regulates food, cosmetics, medicines, and medical devices, also does not have any evidence or research data that ingredients in underarm antiperspirants or deodorants cause cancer." so you can use it! you'll be fine =]
hope this helps! =[ happy holidays! and stay stank free lol!
Reply:Yes, men can get breast cancer but it is rare and usually occurs in older men (those over 60 or so). Also, there is absolutely no scientific evidence to suggest that anti-perspirant causes cancer. That's a myth but there is zero evidence to support that claim.
Reply:Yes. Absolutely.
Cancer can occur anywhere in the body, to anyone regardless of gender, at any age. That's what makes the big C so fearsome. And, there are no symptoms initially and there is no one environmental factor can be pin pointed.
In men the incidence is lot lower than women though. Don't have any particular reason however the scientific community says that testosterone in males being at a higher level may be the reason for lower incidence.
Reply:I heard on tv they can
Reply:Yes, men CAN get breast cancer. I have heard of cases where men did in fact contract it, and needed to undergo surgery and things just as women do.
As for anti perspirant, I'm not quite sure if it causes cancer, although they say nearly everything nowadays does cause cancer. I know a lot of the ingredients in deodorant aren't good for you, which is why a lot of people opt to NOT use deodorant, but to use natural methods.
I hope I provided some type of insight...
Reply:Contrary to macho belief, YES.
Breasts are breasts.
Reply:They sure can.
mortgage loan
Reply:of course men can get breast cancer
here are the symptoms to look for
# hanges to the breast behind the nipple:
- Normally lumps that can be felt
- A firm mass directly underneath the nipple
# Nipples turning inwards
# Discharge from the nipple, which can be bloody
# Pain and itchy nipple
# Skin ulceration
# Lump under the arm
# Redness of the skin.
here are a few questions and answrs which are very interesting
Q: What is the ratio between men and women for survival from breast cancer?
It is said less in men due to poor prognosis.
Q: Why don't men know that they have breast cancer?
Because the majority of men don't know they can get it so ignore the changes or warning signs that would enable them to know. Also most females don't realise that men can get breast cancer.
Q: What percentage of men are diagnosed with breast cancer?
At time of writing (Oct 2005), 1 in 100 or 1%, compared with 1 in 14 women.
Q: Most breast cancer occurs in males aged between the ages of 60 and 70?
Yes. From the little information that does exist, it appears this is the case, but don't let that make you complacent, as Kym (whose story is here in our website) was 45 years old, Troy Smith a Cross Country Coach in Birmingham was 33 years old and Jason Foy from the UK was only 29 years old and sadly died at 33 years in 2004.
Click here to read Kym鈥檚 story.
with regards to anti antiperspirant Aluminum, a common ingredient added to antiperspirants to stop skin sweating, may be linked to breast cancer, a study by British scientists found.
Reply:yes men can although it is rarer in men but there is no evidence that antiperspirant causes cancer
Reply:Yes men can get breast cancer. There is no proof that anti-perspirants cause cancer. No one knows what causes cancer.
Reply:Yes John they can but under arm stuff dont cause it ...
Reply:yes men can defiantly have breast cancer, its just not known because they advertise women breast cancer and women are most likely to have it... There has been tons of warnings circulated through email and the internet that the use of deodorants and antiperspirants can cause breast cancer. The suggestion is that a chemical is absorbed through the skin through a shaving nick or cut, and causes breast cancer.
According to the National Cancer Institute, "researchers at the National Cancer Institute (NCI) are not aware of any conclusive evidence linking the use of underarm antiperspirants or deodorants and the subsequent development of breast cancer. The U.S. Food and Drug Administration, which regulates food, cosmetics, medicines, and medical devices, also does not have any evidence or research data that ingredients in underarm antiperspirants or deodorants cause cancer." so you can use it! you'll be fine =]
hope this helps! =[ happy holidays! and stay stank free lol!
Reply:Yes, men can get breast cancer but it is rare and usually occurs in older men (those over 60 or so). Also, there is absolutely no scientific evidence to suggest that anti-perspirant causes cancer. That's a myth but there is zero evidence to support that claim.
Reply:Yes. Absolutely.
Cancer can occur anywhere in the body, to anyone regardless of gender, at any age. That's what makes the big C so fearsome. And, there are no symptoms initially and there is no one environmental factor can be pin pointed.
In men the incidence is lot lower than women though. Don't have any particular reason however the scientific community says that testosterone in males being at a higher level may be the reason for lower incidence.
Reply:I heard on tv they can
Reply:Yes, men CAN get breast cancer. I have heard of cases where men did in fact contract it, and needed to undergo surgery and things just as women do.
As for anti perspirant, I'm not quite sure if it causes cancer, although they say nearly everything nowadays does cause cancer. I know a lot of the ingredients in deodorant aren't good for you, which is why a lot of people opt to NOT use deodorant, but to use natural methods.
I hope I provided some type of insight...
Reply:Contrary to macho belief, YES.
Breasts are breasts.
Reply:They sure can.
mortgage loan
Why is it important to assess a patient's full medication history b4 commencing a course of cancer therapy?
81>What is the importance of having full medication history before a cancer patient is being treated with anti cancer therapy or supportive care therapy?
Reply:It is always important to assess a patient's full mx history b4 commencing a course of cancer therapy/ supportive care tx because:
1) to prevent drug-drug interaction/ disease-contraindication
2) allergy reaction
3) non-response therapy
Reply:There are some medications that do not react well if they are in the human body at the same time. The product of this reaction can make you sicker than you were to begin with.
Reply:some drugs that are used for treatment arent suitable for everyone so it's important to know a patients full medical history first.
Hope this helps.
Reply:It is always important to assess a patient's full mx history b4 commencing a course of cancer therapy/ supportive care tx because:
1) to prevent drug-drug interaction/ disease-contraindication
2) allergy reaction
3) non-response therapy
Reply:There are some medications that do not react well if they are in the human body at the same time. The product of this reaction can make you sicker than you were to begin with.
Reply:some drugs that are used for treatment arent suitable for everyone so it's important to know a patients full medical history first.
Hope this helps.
What are the best fruits or veggies that could prevent cancer?
80>Or as anti cancer?
Reply:tomatoes eaten along with broccoli
Reply:tomatoes i know help prevent cancer.
Reply:you should check out artemisinin. it is a naturopathic alternative that can be very helpful for either.
Reply:I met an old man that for the last 35 years has been a researcher for cancer and he told me that apricot seeds, green kale, and black walnut is the best previntative for cancer. The apricot seeds are sometimes hard to find. The kale is best eaten raw and the the black walnut is in a capsule form at any health food store. Hope this helps.
Reply:tomatoes eaten along with broccoli
Reply:tomatoes i know help prevent cancer.
Reply:you should check out artemisinin. it is a naturopathic alternative that can be very helpful for either.
Reply:I met an old man that for the last 35 years has been a researcher for cancer and he told me that apricot seeds, green kale, and black walnut is the best previntative for cancer. The apricot seeds are sometimes hard to find. The kale is best eaten raw and the the black walnut is in a capsule form at any health food store. Hope this helps.
Is it true that anti-perspirants and deodorants that contain Aluminum can cause breast cancer?
79>Yes it is true..... It blocks the sweat glands as well which is unhealthy.
A guy I knew, his dad actually had breast cancer as a result of using aluminium based deoderants.
There are some pretty good non-aluminium deoderants out there which work well... just takes a bit of time trying different ones out :)
Reply:No scientific bases for that .
Reply:I've heard that it can cause Alzheimer's. So, you might want to change your deodorant.
A guy I knew, his dad actually had breast cancer as a result of using aluminium based deoderants.
There are some pretty good non-aluminium deoderants out there which work well... just takes a bit of time trying different ones out :)
Reply:No scientific bases for that .
Reply:I've heard that it can cause Alzheimer's. So, you might want to change your deodorant.
Should i ask him if he has prostate cancer?
78>my father went to doctor last month because he had problems with his water works, he got lots of tests and a biopsy of his prostate, when the results got back he told the family that it was just swollen due to hormones, since then he has had a bone scan which he said is a precaution, he is getting hormone injections into his abdomen to reduce the swelling(he says). anyway i was really suspicious so i looked in his medisine drawer and found his injections and looked them up on the net and they are anti cancer, he is obviously not wanting to tell us incase we are upset, i cry nearly every day thinking of it god knows how my mum would react, should i ask him outright and keep the answer from my mum or should i let him tell us in his own time?? he shouldnt have to go through this alone. he is 75 and i understand that he is elderly but you never imagine loosing them do you??
Reply:My thoughts are with you and your Dad. So many times I have heard about this problem. Men of any age find it difficult to talk about health problems - especially those "below the belt". A starting point for you may be to contact a support group. You can share your worries with others who have faced the same problem and can find out more about the problem and the treatment that your Dad is receiving. They are there to listen and support not only your Dad but you too. At any age - he is still your Dad and you will always love him and worry about him. Take care of yourself .... and your Dad too.
I understand all you are feeling - my Dad too had prostate cancer. I found lots of support from our local prostate cancer charity (listed below) and now have joined them and offer support to others who may need it
Reply:if you want ...go for it
Reply:i would wait until he's alone and go and have a quiet chat with him, tell him your really worried about him and he can talk to you if he needs to. Tell him if there was something wrong you would rather know about it. Hope everything is ok, good luck x
Reply:My father is 77 and his prostate cancer is controlled with injections of oestrogen - result: he's somewhat less hairy than he used to be, has put on lots of weight, and is rahter more emotional. But he isn't dead. And nor is your father.
I'd leave him to tell you in his own time - much as in the same way you wish he had done when he found a packet of cigarettes in your jacket pocket when you were 12...
Reply:i would talk to him and tell him that you are worried about him but he could live to be 90 or more my uncles had prostrate cancer and he is having injection and have been for a few years and is fine the doctor told him that it can be controlled but you have to except the fact that our parent will not live forever so take care of your dad and if you are relay worried go and talk to your G P and tell him what you know and he will tell you that your dad could live a long time with what he got as long as he takes medication i relay don't think you should say a word to your mum not yet try not to worry to much just take care of both your mum and dad as they are so precious
Reply:Just let him know you love him. give him lots of hugs and tell him how important he has been to you. A lot of guys that age were raised in the "big boys don't cry" era and may even be embarrassed to talk about the medical issue he is facing. He may even be in denial. Love and acceptance are the keys to getting him to open up when he is ready.
Good luck!
Reply:Why not ask him, its better knowing then not to know......I'm sure he may not mind.
Reply:Sure..... Prevention is better than cure!
Reply:Whilst there is no guarantee I know a number of frineds who have this problem and have had similar treatment which has been very successful.
You could find a 'right' time and talk gently to him, telling him that you realise there is a problem that is being treated and that you are with him all the way - you will find your own words.
Best wishes, James
Reply:I say you should ask him but be gentle about it. It probly wouldn't be smart for you to tell your mother you should suggest to him that he tell your mother.
Reply:Always reverse a situation, would you like to be placed in the position you are thinking of placing your father i.e. in a corner with your question?
He is your father and I'm sure that you love him, therefore respect the fact they at this particular moment he doesn't want to discuss it.
It's his privilege, and it's his body.
Personally,I'd treat him as I always have, as will your mum who is oblivious at present of a possible problem. Leave sleeping dogs lie.
I'm sure your father will thank you for it in the end.
Try not to worry, the older you get cancer the slower it grows, so your father has probably got many years in front of him, especially if he continues with the treatment.
I wish you and your father all the best,god bless.
Paper
Reply:My thoughts are with you and your Dad. So many times I have heard about this problem. Men of any age find it difficult to talk about health problems - especially those "below the belt". A starting point for you may be to contact a support group. You can share your worries with others who have faced the same problem and can find out more about the problem and the treatment that your Dad is receiving. They are there to listen and support not only your Dad but you too. At any age - he is still your Dad and you will always love him and worry about him. Take care of yourself .... and your Dad too.
I understand all you are feeling - my Dad too had prostate cancer. I found lots of support from our local prostate cancer charity (listed below) and now have joined them and offer support to others who may need it
Reply:if you want ...go for it
Reply:i would wait until he's alone and go and have a quiet chat with him, tell him your really worried about him and he can talk to you if he needs to. Tell him if there was something wrong you would rather know about it. Hope everything is ok, good luck x
Reply:My father is 77 and his prostate cancer is controlled with injections of oestrogen - result: he's somewhat less hairy than he used to be, has put on lots of weight, and is rahter more emotional. But he isn't dead. And nor is your father.
I'd leave him to tell you in his own time - much as in the same way you wish he had done when he found a packet of cigarettes in your jacket pocket when you were 12...
Reply:i would talk to him and tell him that you are worried about him but he could live to be 90 or more my uncles had prostrate cancer and he is having injection and have been for a few years and is fine the doctor told him that it can be controlled but you have to except the fact that our parent will not live forever so take care of your dad and if you are relay worried go and talk to your G P and tell him what you know and he will tell you that your dad could live a long time with what he got as long as he takes medication i relay don't think you should say a word to your mum not yet try not to worry to much just take care of both your mum and dad as they are so precious
Reply:Just let him know you love him. give him lots of hugs and tell him how important he has been to you. A lot of guys that age were raised in the "big boys don't cry" era and may even be embarrassed to talk about the medical issue he is facing. He may even be in denial. Love and acceptance are the keys to getting him to open up when he is ready.
Good luck!
Reply:Why not ask him, its better knowing then not to know......I'm sure he may not mind.
Reply:Sure..... Prevention is better than cure!
Reply:Whilst there is no guarantee I know a number of frineds who have this problem and have had similar treatment which has been very successful.
You could find a 'right' time and talk gently to him, telling him that you realise there is a problem that is being treated and that you are with him all the way - you will find your own words.
Best wishes, James
Reply:I say you should ask him but be gentle about it. It probly wouldn't be smart for you to tell your mother you should suggest to him that he tell your mother.
Reply:Always reverse a situation, would you like to be placed in the position you are thinking of placing your father i.e. in a corner with your question?
He is your father and I'm sure that you love him, therefore respect the fact they at this particular moment he doesn't want to discuss it.
It's his privilege, and it's his body.
Personally,I'd treat him as I always have, as will your mum who is oblivious at present of a possible problem. Leave sleeping dogs lie.
I'm sure your father will thank you for it in the end.
Try not to worry, the older you get cancer the slower it grows, so your father has probably got many years in front of him, especially if he continues with the treatment.
I wish you and your father all the best,god bless.
Paper
Sir, I want to know about cancer drugs?
77>how these drugs can provide anti-cancer activity
Reply:Here is some info to get you started.
Chemotherapy
The ideal chemotherapeutic drug would target and destroy only cancer cells. Unfortunately, few such drugs exist. Common chemotherapeutic drugs and their adverse effects are described in Table 2: Principles of Cancer Therapy: Commonly Used Antineoplastic Drugs .
Table 2
Commonly Used Antineoplastic Drugs
This table is presented as a PDF and requires the free Adobe PDF reader. Get Adobe Reader
The most common routes of administration are IV and oral. Frequent dosing for extended periods may necessitate subcutaneously implanted venous access devices (central or peripheral), multilumen external catheters, or peripherally inserted central catheters.
Drug resistance can occur to chemotherapy. Identified mechanisms include overexpression of target genes, drug inactivation by tumor cells, defective apoptosis in tumor cells, and loss of receptors for hormonal agents. One of the best characterized mechanisms is overexpression of the MDR-1 gene, a cell membrane transporter that causes efflux of certain drugs (eg, vinca alkaloids, taxanes, anthracyclines). Attempts to alter MDR-1 function and thus prevent drug resistance have been unsuccessful.
Cytotoxic drugs: Traditional cytotoxic chemotherapy, which damages cell DNA, kills many normal cells in addition to cancer cells. Antimetabolites, such as 5-fluorouracilSome Trade Names
ADRUCIL
Drug Information
and methotrexateSome Trade Names
RHEUMATREX
Drug Information
, are cell cycle鈥搒pecific and have no linear dose-response relationship. In contrast, other chemotherapeutic drugs (eg, DNA cross-linkers, also known as alkylating agents) have a linear dose-response relationship, producing more tumor killing as well as more toxicity at higher doses. At their highest doses, DNA cross-linkers may produce bone marrow aplasia, necessitating bone marrow transplantation to restore bone marrow function.
Single-drug therapy may cure selected cancers (eg, choriocarcinoma, hairy cell leukemia). More commonly, multidrug regimens incorporating drugs with different mechanisms of action and different toxicities are used to increase the tumor cell kill, reduce dose-related toxicity, and decrease the probability of drug resistance. These regimens can provide significant cure rates (eg, in acute leukemia, testicular cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, and, less commonly, solid tumors such as small cell lung cancer and nasopharyngeal cancer). Multidrug regimens typically are given as repetitive cycles of a fixed combination of drugs. The interval between cycles should be the shortest one that allows for recovery of normal tissue. Continuous infusion may increase cell kill with some cell cycle-specific drugs (eg, 5-fluorouracilSome Trade Names
ADRUCIL
Drug Information
).
For each patient, the probability of significant toxicities should be weighed against the likelihood of benefit. End-organ function should be assessed before chemotherapeutic drugs with organ-specific toxicities are used (eg, echocardiography before doxorubicinSome Trade Names
ADRIAMYCIN
Drug Information
use). Dose modification or exclusion of certain drugs may be necessary in patients with chronic lung disease (eg, bleomycinSome Trade Names
BLENOXANE
Drug Information
), renal failure (eg, methotrexateSome Trade Names
RHEUMATREX
Drug Information
), or hepatic dysfunction (eg, taxanes).
Despite these precautions, adverse effects commonly result from cytotoxic chemotherapy. The normal tissues most commonly affected are those with the highest intrinsic turnover rate: bone marrow, hair follicles, and the GI epithelium.
Imaging (eg, CT, MRI, PET) is frequently performed after 2 to 3 cycles of therapy to evaluate response to treatment. Therapy continues if a clear response is seen. If the tumor progresses despite therapy, the regimen is often amended or stopped. If the disease remains stable with treatment and the patient can tolerate therapy, then a decision to continue is reasonable with the understanding that the disease will eventually progress.
Hormonal therapy: Hormonal therapy uses hormone agonists or antagonists to influence the course of cancer. It may be used alone or in combination with other treatment modalities.
Hormonal therapy is particularly useful in prostate cancer, which grows in response to testosteroneSome Trade Names
DELATESTRYL
Drug Information
. Other cancers with hormone receptors on their cells (eg, breast, endometrium) can often be palliated by hormone antagonist therapy or hormone ablation.
Use of prednisoneSome Trade Names
DELTASONE
Drug Information
, a glucocorticosteroid, is also considered hormonal therapy. It is frequently used to treat tumors derived from the immune system (lymphomas, lymphocytic leukemias, multiple myeloma).
Biologic response modifiers: Interferons are proteins synthesized by cells of the immune system as a physiologic immune protective response to foreign antigens (viruses, bacteria, other foreign cells). In pharmacologic amounts, they can palliate some cancers, including hairy cell leukemia, chronic myelocytic leukemia, locally advanced melanoma, metastatic renal cell cancer, and Kaposi's sarcoma. Significant toxic effects of interferon include fatigue, depression, nausea, leukopenia, chills and fever, and myalgias.
Interleukins, primarily the lymphokine IL-2 produced by activated T cells, can be used in metastatic melanomas and can provide modest palliation in renal cell cancer.
Differentiating drugs: These drugs induce differentiation in cancer cells. All-trans-retinoic acid has been highly effective in treating acute promyelocytic leukemia. Other drugs in this class, including phenylbutyrate, phenylacetate, arsenic compounds, vitamin D analogs, and the hypomethylating agent de-oxyazacytidine, are under study. When used alone, these drugs have only transient effects, but their role in prevention and in combination with cytotoxic drugs is promising.
Antiangiogenesis drugs: Solid tumors produce growth factors that form new blood vessels necessary to support ongoing tumor growth. Several drugs that inhibit this process are available. Thalidomide is antiangiogenic, among its many effects. Avastin, a monoclonal antibody to vascular endothelial growth factor (VEGF), is effective against renal cancers and colon cancer.
Signal transduction inhibitors: Many epithelial tumors possess mutations that activate signaling pathways that contribute to their continuous proliferation and failure to differentiate. These mutated pathways include growth factors and the downstream proteins that transmit messages from growth factor receptors on the cell surface. Two such drugs, imatinibSome Trade Names
GLEEVEC
Drug Information
(an inhibitor of the Bcr-Abl tyrosine kinase in chronic myelocytic leukemia) and erlotinib (an inhibitor of the epidermal growth factor receptor), are now in routine clinical use. Other inhibitors of these signaling pathways are under study.
Monoclonal antibodies: Monoclonal antibodies directed against unique tumor antigens have some efficacy against neoplastic tissue (see also Tumor Immunology: Passive Humoral Immunotherapy). TrastuzumabSome Trade Names
HERCEPTIN
Drug Information
, an antibody directed against a protein called Her-2 or Erb-B2, plus chemotherapy has shown benefit in metastatic breast cancer. Antibodies against CD antigens expressed on neoplastic cells, such as CD20 and CD33, are used to treat patients with non-Hodgkin lymphoma (rituximabSome Trade Names
RITUXAN
Drug Information
, anti-CD20 antibody) and acute myelocytic leukemia (gemtuzumab, an antibody linked to a potent toxin).
The effectiveness of monoclonal antibodies may be increased by linking them to radioactive nuclide. One such drug, ibritumomab, is used to treat non-Hodgkin lymphoma.
Reply:there r many cancer drugs available. keemo therapy is the best option for cancer. this treatement kills the bads cells but it has many side effects.
Reply:Cancer
By Dr.Rangadhar Satpathy
Cancer is a cellular malfunction.
Noni鈥檚 effect to cure cancer work in cellular level.
The sooner a cancer is detected, the greater the chance of remission.
Noni helps to fight the cancer in the following way
(A) By its anti carcinogenic agent
Noni juice contains 150 neutraceuticals. Among them six have been shown to fight cancer.
(1) Polysaccharides
Polysaccharides are found abundant in Noni. Polysaccharides block the adhesion of mutated cells to other cells, so stopping metastasis. Blocking the adhesion of mutated cells to new cell depends on the density of the polysaccharides sulphate groups, their mol.wt and their carbohydrate structure.
(2) Anthraquinones
鈥amnacanthal, an anthraquinone inhibits the growth of malignant cells.
鈥lizarin, another antraquinone block the blood circulation to the malignant tumors, hence prevents its growth.
鈥nthraquinone reduces the cytochrome c (a hem protein whose main function is electron transport using the hem prosthetic group. It act as a cancer causing agent in the body) inside the body without causing the formation of any new free radicals. (Source 鈥?from the research study conducted by group of scientist in Japan 1990)
(3) Epigollocatechin gallate (EGCg)
鈥GCg is a polyphenolic flavonoid antioxidant found in abundant in Noni.
鈥GCg prevent the growth of malignant cells and so induce apoptosis.
鈥n cancer cell the enzyme NOX is active all time. In normal cell the NOX is only active during cell division in response to Growth hormone signal. The EGCg interferes the tumor associated activity of NOX. (Source 鈥?From the research study on Noni juice)
(3) Terpenes compound :
鈥t helps in preventing the proliferation of malignant cells and induces apoptosis.
鈥imonene one terpens has been shown to prevent mammary, liver, lungs carcinoma and also may be effective in treating leukemia.
鈥eta carotene, other terpenes helps to stimulate thymus gland to secrete more T- cells that destroys the carcinoma cells.
鈥rsolic acid, one terpen compound has anti carcinogenic effect both externally and internally to prevent the growth of cancerous cell and inducing apoptosis. (Source- research conducted by the National Cancer Institute, Finland)
(4) Proxeronine
Dr.Heinicke鈥檚 theory suggests that xeronine (conversion from proxeronine by the enzyme proxeroninase) combines with various biochemical鈥檚 and building blocks i.e. hormones, proteins, enzymes, serotonins, vitamins, minerals and antioxidants in intracellular level. The Golgi apparatus and reticuloendothelium then assemble the necessary compounds into a specific 鈥榩ackage鈥?鈥?that 鈥榩ackage鈥?is sent from healthy cells to deranged cells to help in regeneration or rebuild the damaged cells.
Sqamous cell carcinoma
Noni helps to prevents proliferation of cancer cell %26amp; Hence prevents cell mitosis
(B) Modulating the body Immune process.
Noni helps to modulate the production, activity and effectiveness of some immune system agent. That are 鈥?br>
鈥?Nitric Oxide:
Nitric Oxide is produced by activated macrophages plays a role in the host protection against pathogen as well as malignant tumor. Noni increases the body鈥檚 biosynthesis of nitric oxide
鈥?Interleukin:
Noni modulate the production, activity and effectiveness of interleukin-2 that enhances the production of B-cell antibodies and also the cytotoxicity character of Natural Killer (NK) cells.
鈥?Interleukins:
Noni modulate the production %26amp; activity of interferon-y that helps in the activation of macrophages and the over all process of cell mediated immunity. (Source- Dr.Hirajumi report)
鈥?Tumor necrosis factor (TNF):
Tumor necrosis factor from various macrophages destroys the malignant cells. Noni modulate the production, activity of TNF from the macrophages
鈥?Lipopolysachrides (LPS):
The LPS in serum stimulate the body鈥檚 immune process to eliminate any pathogens. Noni help to modulate the production of LPS in serum thus increases the immune process of the body.
鈥?Natural killer cells (NK cells):
Noni helps to modulate the production of NK cells that destroys the malignant cells.
Thus Noni juice is multifaceted in its approach to fight cancer.
Reply:Often Cancer is suffered by those who donot believe in the concept of self present within each of us and are instead often rational or very religious. once they start believing in their self and allow the self to take over their problem through meditation, internal repair starts and cancer vanishes from their system without any trace in a short period.
Reply:Try Vitamin C therapy. A few years ago a cancer researcher came out with a paper saying that the best cancer and infection fighter as yet found was Interferon, but, at the time, it cost $15,000 a gram. The good part was that Interferon was a product of the natural breakdown of Vitamin C in your system. Shortly after that paper came out the FDA tried to make Vit C by prescription only. Guess why? The FDA says that the RDA for Vit C is 64 mg a day, just enough to prevent scurvy. Linus Pauling, who got a Nobel Prize for his work with Vit C and a second Nobel Prize for organic chemistry, said 1000 mg a day as a minimum and 2000 mg a day if you are sick. On a personal note, I was sick twice a year, for 2 weeks at a time, for 20 years, and was flat on my back for at least a week each time. To this day the doctors have no idea what the problem was. After I gave up on the doctors I tried Vit C. I took enough to keep from being sick and just below too much to get diarrhea. It followed a bell curve over 2 weeks with a peak at 40,000 mg a day 鈥?about 300,000 over the 2 weeks. I was not sick for those 2 weeks and after a couple of years of that I have not been sick since. I did not dissolve my kidneys, as some doctors said would happen. I did not get any calcium build up or stones and did not dissolve my cones or solidify my joints. Try it, but drink a lot of water 鈥?Vit C is a natural diuretic.
Reply:Here's an answer in simpler terms:
There are several categories of anti-cancer drugs. Chemotherapy, moncolonal antibodies and, immunotherapy work by killing cancer cells. Differentiation agents, hormone therapy and, targeted therapies work by addressing cancer specific proteins. I will briefly supply a description of each and the mechanism they use.
Chemotherapy drugs can usely be classified as alkylating agents or anti-metabolites. These drugs are taken in by cells that are actively dividing. Both healthy and cancerous cells divide. While some healthy cells (hair, digestive tract lining, blood cells) divide rapidly, most cancerous cells divide much more often. So, they are impacted greater. For anti-metabolites, these drugs are chemically similar to nutrients used by cells. So, cells are fooled to taking in the chemotherapy. Alkylating agents are believed to cross-link DNA. When the cancer cell tries to divide, it cannot overcome the damage and commits suicide (apoptosis). Cancer cells tend to mutate and develop resistance to chemotherapy. This is usually though little pumps called gycloproteins which prevent the chemotherapy drugs from making it to the nucleus. Chemotherapy is used for all types of cancer. Side effects vary and can be harsh.
Monoclonal antibodies are antibodies that were derived from a single line (hence "mono"). Like normal antibodies, these antibodies recognize a specific antigen on the surface of cancer. These monclonal antibodies are linked to either a cytotoxin (cell poison) or a radioactive isotope to kill the cancer cells. Since normal cells do not possess the targeted antigen, they do not bind with the monoclonal antibodies. As mentioned, cancer cells mutate. They may develop a mechanism to fight off the antibodies or lose the antigen signature. Monoclonal antibodies are often used for lymphomas. Because they do not attack healthy cell, the side effects are often mild.
Immunotherapy involves vaccines and/or interferon. The idea is to remove a part of the tumor and some white blood cells. Train the white blood cells to recognize and attack the cancer cells as foreign. Interferon enhances the immune response. As noted, cancers mutate and may lose no longer be recognized by the vaccine. Immunotherapy is used for melamona, kidney cancer and, some sarcomas but, is mostly experimental in other cancers. Side effects can be like a severe flu.
Differentiation agents are drugs used to cause a cancer cell to become mature and functional. Cancer cells start as stem cells that do not differentiate into mature cells. Because of this, they are often not functional (unable to perform the normal function like fight infection for immature white blood cells). Only in AML type 3 (APL), are differentiation agents used as first line therapy. All Trans-Retinoic Acid (ATRA) causes the myeloid to mature. As mature cells, they are fully function to normal cells. Because they do not attack healthy cell, the side effects are often mild.
Hormone therapy is used to block production and/or binding of certain hormones normally produced by the body. These hormones are growth factors signalling cancer cells to divide. Hormone therapy is usually used adjuvant to chemotherapy or as prevention of recurrence if the patient has the gene that indicates the their tumor is hormone receptive. Hormone therapy is used mainly in breast cancer and prostate cancer. It is being tried experimentally in other cancers such as gliomas. Side effects can include menopause which can be severe.
Targeted therapies are drugs which bind to proteins produced by the cancerous cells. These oncoproteins are signals for the cell to divide or other function like recruit blood vessels (angiogenesis). These targeted therapies bind to growth factors with a much greater affinity than the tumor produced growth factors. The side effects of targeted therapies are typically mild. Unfortunately, identifying an oncoprotein and developing a binding agent can be difficult. Some of the more successful targeted therapies (Gleevec, Sprycel and, Tasigna) have produced excellent remission rates for Ph+ CML and ALL and GIST. Other targeted therapies target blood supply recruitment like Avastin, Erbitux, Iressa and, Tarceva have produced survival benefit for some to most patients.
Reply:http://www.webmd.com/cancer/default.htm
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Reply:Are you suffering with cancer if not why you want to know about the drugs stop thinking about any think which is not related to you to have knowledge is good but any thing too much is too bad for you ok
Reply:Here is some info to get you started.
Chemotherapy
The ideal chemotherapeutic drug would target and destroy only cancer cells. Unfortunately, few such drugs exist. Common chemotherapeutic drugs and their adverse effects are described in Table 2: Principles of Cancer Therapy: Commonly Used Antineoplastic Drugs .
Table 2
Commonly Used Antineoplastic Drugs
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The most common routes of administration are IV and oral. Frequent dosing for extended periods may necessitate subcutaneously implanted venous access devices (central or peripheral), multilumen external catheters, or peripherally inserted central catheters.
Drug resistance can occur to chemotherapy. Identified mechanisms include overexpression of target genes, drug inactivation by tumor cells, defective apoptosis in tumor cells, and loss of receptors for hormonal agents. One of the best characterized mechanisms is overexpression of the MDR-1 gene, a cell membrane transporter that causes efflux of certain drugs (eg, vinca alkaloids, taxanes, anthracyclines). Attempts to alter MDR-1 function and thus prevent drug resistance have been unsuccessful.
Cytotoxic drugs: Traditional cytotoxic chemotherapy, which damages cell DNA, kills many normal cells in addition to cancer cells. Antimetabolites, such as 5-fluorouracilSome Trade Names
ADRUCIL
Drug Information
and methotrexateSome Trade Names
RHEUMATREX
Drug Information
, are cell cycle鈥搒pecific and have no linear dose-response relationship. In contrast, other chemotherapeutic drugs (eg, DNA cross-linkers, also known as alkylating agents) have a linear dose-response relationship, producing more tumor killing as well as more toxicity at higher doses. At their highest doses, DNA cross-linkers may produce bone marrow aplasia, necessitating bone marrow transplantation to restore bone marrow function.
Single-drug therapy may cure selected cancers (eg, choriocarcinoma, hairy cell leukemia). More commonly, multidrug regimens incorporating drugs with different mechanisms of action and different toxicities are used to increase the tumor cell kill, reduce dose-related toxicity, and decrease the probability of drug resistance. These regimens can provide significant cure rates (eg, in acute leukemia, testicular cancer, Hodgkin lymphoma, non-Hodgkin lymphoma, and, less commonly, solid tumors such as small cell lung cancer and nasopharyngeal cancer). Multidrug regimens typically are given as repetitive cycles of a fixed combination of drugs. The interval between cycles should be the shortest one that allows for recovery of normal tissue. Continuous infusion may increase cell kill with some cell cycle-specific drugs (eg, 5-fluorouracilSome Trade Names
ADRUCIL
Drug Information
).
For each patient, the probability of significant toxicities should be weighed against the likelihood of benefit. End-organ function should be assessed before chemotherapeutic drugs with organ-specific toxicities are used (eg, echocardiography before doxorubicinSome Trade Names
ADRIAMYCIN
Drug Information
use). Dose modification or exclusion of certain drugs may be necessary in patients with chronic lung disease (eg, bleomycinSome Trade Names
BLENOXANE
Drug Information
), renal failure (eg, methotrexateSome Trade Names
RHEUMATREX
Drug Information
), or hepatic dysfunction (eg, taxanes).
Despite these precautions, adverse effects commonly result from cytotoxic chemotherapy. The normal tissues most commonly affected are those with the highest intrinsic turnover rate: bone marrow, hair follicles, and the GI epithelium.
Imaging (eg, CT, MRI, PET) is frequently performed after 2 to 3 cycles of therapy to evaluate response to treatment. Therapy continues if a clear response is seen. If the tumor progresses despite therapy, the regimen is often amended or stopped. If the disease remains stable with treatment and the patient can tolerate therapy, then a decision to continue is reasonable with the understanding that the disease will eventually progress.
Hormonal therapy: Hormonal therapy uses hormone agonists or antagonists to influence the course of cancer. It may be used alone or in combination with other treatment modalities.
Hormonal therapy is particularly useful in prostate cancer, which grows in response to testosteroneSome Trade Names
DELATESTRYL
Drug Information
. Other cancers with hormone receptors on their cells (eg, breast, endometrium) can often be palliated by hormone antagonist therapy or hormone ablation.
Use of prednisoneSome Trade Names
DELTASONE
Drug Information
, a glucocorticosteroid, is also considered hormonal therapy. It is frequently used to treat tumors derived from the immune system (lymphomas, lymphocytic leukemias, multiple myeloma).
Biologic response modifiers: Interferons are proteins synthesized by cells of the immune system as a physiologic immune protective response to foreign antigens (viruses, bacteria, other foreign cells). In pharmacologic amounts, they can palliate some cancers, including hairy cell leukemia, chronic myelocytic leukemia, locally advanced melanoma, metastatic renal cell cancer, and Kaposi's sarcoma. Significant toxic effects of interferon include fatigue, depression, nausea, leukopenia, chills and fever, and myalgias.
Interleukins, primarily the lymphokine IL-2 produced by activated T cells, can be used in metastatic melanomas and can provide modest palliation in renal cell cancer.
Differentiating drugs: These drugs induce differentiation in cancer cells. All-trans-retinoic acid has been highly effective in treating acute promyelocytic leukemia. Other drugs in this class, including phenylbutyrate, phenylacetate, arsenic compounds, vitamin D analogs, and the hypomethylating agent de-oxyazacytidine, are under study. When used alone, these drugs have only transient effects, but their role in prevention and in combination with cytotoxic drugs is promising.
Antiangiogenesis drugs: Solid tumors produce growth factors that form new blood vessels necessary to support ongoing tumor growth. Several drugs that inhibit this process are available. Thalidomide is antiangiogenic, among its many effects. Avastin, a monoclonal antibody to vascular endothelial growth factor (VEGF), is effective against renal cancers and colon cancer.
Signal transduction inhibitors: Many epithelial tumors possess mutations that activate signaling pathways that contribute to their continuous proliferation and failure to differentiate. These mutated pathways include growth factors and the downstream proteins that transmit messages from growth factor receptors on the cell surface. Two such drugs, imatinibSome Trade Names
GLEEVEC
Drug Information
(an inhibitor of the Bcr-Abl tyrosine kinase in chronic myelocytic leukemia) and erlotinib (an inhibitor of the epidermal growth factor receptor), are now in routine clinical use. Other inhibitors of these signaling pathways are under study.
Monoclonal antibodies: Monoclonal antibodies directed against unique tumor antigens have some efficacy against neoplastic tissue (see also Tumor Immunology: Passive Humoral Immunotherapy). TrastuzumabSome Trade Names
HERCEPTIN
Drug Information
, an antibody directed against a protein called Her-2 or Erb-B2, plus chemotherapy has shown benefit in metastatic breast cancer. Antibodies against CD antigens expressed on neoplastic cells, such as CD20 and CD33, are used to treat patients with non-Hodgkin lymphoma (rituximabSome Trade Names
RITUXAN
Drug Information
, anti-CD20 antibody) and acute myelocytic leukemia (gemtuzumab, an antibody linked to a potent toxin).
The effectiveness of monoclonal antibodies may be increased by linking them to radioactive nuclide. One such drug, ibritumomab, is used to treat non-Hodgkin lymphoma.
Reply:there r many cancer drugs available. keemo therapy is the best option for cancer. this treatement kills the bads cells but it has many side effects.
Reply:Cancer
By Dr.Rangadhar Satpathy
Cancer is a cellular malfunction.
Noni鈥檚 effect to cure cancer work in cellular level.
The sooner a cancer is detected, the greater the chance of remission.
Noni helps to fight the cancer in the following way
(A) By its anti carcinogenic agent
Noni juice contains 150 neutraceuticals. Among them six have been shown to fight cancer.
(1) Polysaccharides
Polysaccharides are found abundant in Noni. Polysaccharides block the adhesion of mutated cells to other cells, so stopping metastasis. Blocking the adhesion of mutated cells to new cell depends on the density of the polysaccharides sulphate groups, their mol.wt and their carbohydrate structure.
(2) Anthraquinones
鈥amnacanthal, an anthraquinone inhibits the growth of malignant cells.
鈥lizarin, another antraquinone block the blood circulation to the malignant tumors, hence prevents its growth.
鈥nthraquinone reduces the cytochrome c (a hem protein whose main function is electron transport using the hem prosthetic group. It act as a cancer causing agent in the body) inside the body without causing the formation of any new free radicals. (Source 鈥?from the research study conducted by group of scientist in Japan 1990)
(3) Epigollocatechin gallate (EGCg)
鈥GCg is a polyphenolic flavonoid antioxidant found in abundant in Noni.
鈥GCg prevent the growth of malignant cells and so induce apoptosis.
鈥n cancer cell the enzyme NOX is active all time. In normal cell the NOX is only active during cell division in response to Growth hormone signal. The EGCg interferes the tumor associated activity of NOX. (Source 鈥?From the research study on Noni juice)
(3) Terpenes compound :
鈥t helps in preventing the proliferation of malignant cells and induces apoptosis.
鈥imonene one terpens has been shown to prevent mammary, liver, lungs carcinoma and also may be effective in treating leukemia.
鈥eta carotene, other terpenes helps to stimulate thymus gland to secrete more T- cells that destroys the carcinoma cells.
鈥rsolic acid, one terpen compound has anti carcinogenic effect both externally and internally to prevent the growth of cancerous cell and inducing apoptosis. (Source- research conducted by the National Cancer Institute, Finland)
(4) Proxeronine
Dr.Heinicke鈥檚 theory suggests that xeronine (conversion from proxeronine by the enzyme proxeroninase) combines with various biochemical鈥檚 and building blocks i.e. hormones, proteins, enzymes, serotonins, vitamins, minerals and antioxidants in intracellular level. The Golgi apparatus and reticuloendothelium then assemble the necessary compounds into a specific 鈥榩ackage鈥?鈥?that 鈥榩ackage鈥?is sent from healthy cells to deranged cells to help in regeneration or rebuild the damaged cells.
Sqamous cell carcinoma
Noni helps to prevents proliferation of cancer cell %26amp; Hence prevents cell mitosis
(B) Modulating the body Immune process.
Noni helps to modulate the production, activity and effectiveness of some immune system agent. That are 鈥?br>
鈥?Nitric Oxide:
Nitric Oxide is produced by activated macrophages plays a role in the host protection against pathogen as well as malignant tumor. Noni increases the body鈥檚 biosynthesis of nitric oxide
鈥?Interleukin:
Noni modulate the production, activity and effectiveness of interleukin-2 that enhances the production of B-cell antibodies and also the cytotoxicity character of Natural Killer (NK) cells.
鈥?Interleukins:
Noni modulate the production %26amp; activity of interferon-y that helps in the activation of macrophages and the over all process of cell mediated immunity. (Source- Dr.Hirajumi report)
鈥?Tumor necrosis factor (TNF):
Tumor necrosis factor from various macrophages destroys the malignant cells. Noni modulate the production, activity of TNF from the macrophages
鈥?Lipopolysachrides (LPS):
The LPS in serum stimulate the body鈥檚 immune process to eliminate any pathogens. Noni help to modulate the production of LPS in serum thus increases the immune process of the body.
鈥?Natural killer cells (NK cells):
Noni helps to modulate the production of NK cells that destroys the malignant cells.
Thus Noni juice is multifaceted in its approach to fight cancer.
Reply:Often Cancer is suffered by those who donot believe in the concept of self present within each of us and are instead often rational or very religious. once they start believing in their self and allow the self to take over their problem through meditation, internal repair starts and cancer vanishes from their system without any trace in a short period.
Reply:Try Vitamin C therapy. A few years ago a cancer researcher came out with a paper saying that the best cancer and infection fighter as yet found was Interferon, but, at the time, it cost $15,000 a gram. The good part was that Interferon was a product of the natural breakdown of Vitamin C in your system. Shortly after that paper came out the FDA tried to make Vit C by prescription only. Guess why? The FDA says that the RDA for Vit C is 64 mg a day, just enough to prevent scurvy. Linus Pauling, who got a Nobel Prize for his work with Vit C and a second Nobel Prize for organic chemistry, said 1000 mg a day as a minimum and 2000 mg a day if you are sick. On a personal note, I was sick twice a year, for 2 weeks at a time, for 20 years, and was flat on my back for at least a week each time. To this day the doctors have no idea what the problem was. After I gave up on the doctors I tried Vit C. I took enough to keep from being sick and just below too much to get diarrhea. It followed a bell curve over 2 weeks with a peak at 40,000 mg a day 鈥?about 300,000 over the 2 weeks. I was not sick for those 2 weeks and after a couple of years of that I have not been sick since. I did not dissolve my kidneys, as some doctors said would happen. I did not get any calcium build up or stones and did not dissolve my cones or solidify my joints. Try it, but drink a lot of water 鈥?Vit C is a natural diuretic.
Reply:Here's an answer in simpler terms:
There are several categories of anti-cancer drugs. Chemotherapy, moncolonal antibodies and, immunotherapy work by killing cancer cells. Differentiation agents, hormone therapy and, targeted therapies work by addressing cancer specific proteins. I will briefly supply a description of each and the mechanism they use.
Chemotherapy drugs can usely be classified as alkylating agents or anti-metabolites. These drugs are taken in by cells that are actively dividing. Both healthy and cancerous cells divide. While some healthy cells (hair, digestive tract lining, blood cells) divide rapidly, most cancerous cells divide much more often. So, they are impacted greater. For anti-metabolites, these drugs are chemically similar to nutrients used by cells. So, cells are fooled to taking in the chemotherapy. Alkylating agents are believed to cross-link DNA. When the cancer cell tries to divide, it cannot overcome the damage and commits suicide (apoptosis). Cancer cells tend to mutate and develop resistance to chemotherapy. This is usually though little pumps called gycloproteins which prevent the chemotherapy drugs from making it to the nucleus. Chemotherapy is used for all types of cancer. Side effects vary and can be harsh.
Monoclonal antibodies are antibodies that were derived from a single line (hence "mono"). Like normal antibodies, these antibodies recognize a specific antigen on the surface of cancer. These monclonal antibodies are linked to either a cytotoxin (cell poison) or a radioactive isotope to kill the cancer cells. Since normal cells do not possess the targeted antigen, they do not bind with the monoclonal antibodies. As mentioned, cancer cells mutate. They may develop a mechanism to fight off the antibodies or lose the antigen signature. Monoclonal antibodies are often used for lymphomas. Because they do not attack healthy cell, the side effects are often mild.
Immunotherapy involves vaccines and/or interferon. The idea is to remove a part of the tumor and some white blood cells. Train the white blood cells to recognize and attack the cancer cells as foreign. Interferon enhances the immune response. As noted, cancers mutate and may lose no longer be recognized by the vaccine. Immunotherapy is used for melamona, kidney cancer and, some sarcomas but, is mostly experimental in other cancers. Side effects can be like a severe flu.
Differentiation agents are drugs used to cause a cancer cell to become mature and functional. Cancer cells start as stem cells that do not differentiate into mature cells. Because of this, they are often not functional (unable to perform the normal function like fight infection for immature white blood cells). Only in AML type 3 (APL), are differentiation agents used as first line therapy. All Trans-Retinoic Acid (ATRA) causes the myeloid to mature. As mature cells, they are fully function to normal cells. Because they do not attack healthy cell, the side effects are often mild.
Hormone therapy is used to block production and/or binding of certain hormones normally produced by the body. These hormones are growth factors signalling cancer cells to divide. Hormone therapy is usually used adjuvant to chemotherapy or as prevention of recurrence if the patient has the gene that indicates the their tumor is hormone receptive. Hormone therapy is used mainly in breast cancer and prostate cancer. It is being tried experimentally in other cancers such as gliomas. Side effects can include menopause which can be severe.
Targeted therapies are drugs which bind to proteins produced by the cancerous cells. These oncoproteins are signals for the cell to divide or other function like recruit blood vessels (angiogenesis). These targeted therapies bind to growth factors with a much greater affinity than the tumor produced growth factors. The side effects of targeted therapies are typically mild. Unfortunately, identifying an oncoprotein and developing a binding agent can be difficult. Some of the more successful targeted therapies (Gleevec, Sprycel and, Tasigna) have produced excellent remission rates for Ph+ CML and ALL and GIST. Other targeted therapies target blood supply recruitment like Avastin, Erbitux, Iressa and, Tarceva have produced survival benefit for some to most patients.
Reply:http://www.webmd.com/cancer/default.htm
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Reply:Are you suffering with cancer if not why you want to know about the drugs stop thinking about any think which is not related to you to have knowledge is good but any thing too much is too bad for you ok
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